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Increased "absence" of telomeres may indicate Alzheimer's disease/dementia status in older individuals with Down syndrome.
Jenkins EC, Ye L, Gu H, Ni SA, Duncan CJ, Velinov M, Pang D, Krinsky-McHale SJ, Zigman WB, Schupf N, Silverman WP. Jenkins EC, et al. Among authors: gu h. Neurosci Lett. 2008 Aug 8;440(3):340-3. doi: 10.1016/j.neulet.2008.05.098. Epub 2008 Jun 18. Neurosci Lett. 2008. PMID: 18571319 Free PMC article.
We have reported previously that telomeres (ends of chromosomes consisting of highly conserved TTAGGG repeats) were shorter in metaphase and interphase preparations in T lymphocytes from short-term whole blood cultures of women with Down syndrome (DS) and dementia compared to age …
We have reported previously that telomeres (ends of chromosomes consisting of highly conserved TTAGGG repeats) were shorter in metaphase and …
Successful aging in a 70-year-old man with down syndrome: a case study.
Krinsky-McHale SJ, Devenny DA, Gu H, Jenkins EC, Kittler P, Murty VV, Schupf N, Scotto L, Tycko B, Urv TK, Ye L, Zigman WB, Silverman W. Krinsky-McHale SJ, et al. Among authors: gu h. Intellect Dev Disabil. 2008 Jun;46(3):215-28. doi: 10.1352/2008.46:215-228. Intellect Dev Disabil. 2008. PMID: 18578579
Mitotic index and Alzheimer's disease.
Jenkins EC, Ye L, Gu H, Wisniewski HM. Jenkins EC, et al. Among authors: gu h. Neuroreport. 1998 Dec 1;9(17):3857-61. doi: 10.1097/00001756-199812010-00017. Neuroreport. 1998. PMID: 9875718
6,598 results