Sim SC - Search Results

1

CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele.

Sim SC, Edwards RJ, Boobis AR, Ingelman-Sundberg M. Sim SC, et al. Pharmacogenet Genomics. 2005 Sep;15(9):625-31. doi: 10.1097/01.fpc.0000171516.84139.89. Pharmacogenet Genomics. 2005. PMID: 16041241

2

The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects.

Sim SC, Ingelman-Sundberg M. Sim SC, et al. Hum Genomics. 2010 Apr;4(4):278-81. doi: 10.1186/1479-7364-4-4-278. Hum Genomics. 2010. PMID: 20511141 Free PMC article.

3

Intronic polymorphisms of cytochromes P450.

Ingelman-Sundberg M, Sim SC. Ingelman-Sundberg M, et al. Among authors: sim sc. Hum Genomics. 2010 Aug;4(6):402-5. doi: 10.1186/1479-7364-4-6-402. Hum Genomics. 2010. PMID: 20846929 Free PMC article.

4

Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene.

Persson A, Sim SC, Virding S, Onishchenko N, Schulte G, Ingelman-Sundberg M. Persson A, et al. Among authors: sim sc. Mol Psychiatry. 2014 Jun;19(6):733-41. doi: 10.1038/mp.2013.89. Epub 2013 Jul 23. Mol Psychiatry. 2014. PMID: 23877834 Free PMC article.

5

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.

Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, Ingelman-Sundberg M. Sim SC, et al. Clin Pharmacol Ther. 2006 Jan;79(1):103-13. doi: 10.1016/j.clpt.2005.10.002. Clin Pharmacol Ther. 2006. PMID: 16413245

6

The human cytochrome P450 Allele Nomenclature Committee Web site: submission criteria, procedures, and objectives.

Sim SC, Ingelman-Sundberg M. Sim SC, et al. Methods Mol Biol. 2006;320:183-91. doi: 10.1385/1-59259-998-2:183. Methods Mol Biol. 2006. PMID: 16719391

7

Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects.

Ohlsson Rosenborg S, Mwinyi J, Andersson M, Baldwin RM, Pedersen RS, Sim SC, Bertilsson L, Ingelman-Sundberg M, Eliasson E. Ohlsson Rosenborg S, et al. Among authors: sim sc. Eur J Clin Pharmacol. 2008 Dec;64(12):1175-9. doi: 10.1007/s00228-008-0529-z. Epub 2008 Jul 25. Eur J Clin Pharmacol. 2008. PMID: 18654768 Clinical Trial.

8

Association between CYP2C19 polymorphism and depressive symptoms.

Sim SC, Nordin L, Andersson TM, Virding S, Olsson M, Pedersen NL, Ingelman-Sundberg M. Sim SC, et al. Am J Med Genet B Neuropsychiatr Genet. 2010 Sep;153B(6):1160-6. doi: 10.1002/ajmg.b.31081. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 20468063

9

Pharmacogenetic biomarkers as tools for improved drug therapy; emphasis on the cytochrome P450 system.

Ingelman-Sundberg M, Sim SC. Ingelman-Sundberg M, et al. Among authors: sim sc. Biochem Biophys Res Commun. 2010 May 21;396(1):90-4. doi: 10.1016/j.bbrc.2010.02.162. Biochem Biophys Res Commun. 2010. PMID: 20494117 Review.

10

Institutional profile: Karolinska Institutet.

Eliasson E, Sim SC, Rane A, Ingelman-Sundberg M. Eliasson E, et al. Among authors: sim sc. Pharmacogenomics. 2012 Dec;13(16):1887-91. doi: 10.2217/pgs.12.176. Pharmacogenomics. 2012. PMID: 23215881

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