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The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.
Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. Schessl C, et al. Among authors: rosten pm. J Clin Invest. 2005 Aug;115(8):2159-68. doi: 10.1172/JCI24225. Epub 2005 Jul 14. J Clin Invest. 2005. PMID: 16025155 Free PMC article.
Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13.
Imren S, Heuser M, Gasparetto M, Beer PA, Norddahl GL, Xiang P, Chen L, Berg T, Rhyasen GW, Rosten P, Park G, Moon Y, Weng AP, Eaves CJ, Humphries RK. Imren S, et al. Blood. 2014 Dec 4;124(24):3608-12. doi: 10.1182/blood-2014-04-564666. Epub 2014 Oct 22. Blood. 2014. PMID: 25339361 Free PMC article.
Meis2 as a critical player in MN1-induced leukemia.
Lai CK, Norddahl GL, Maetzig T, Rosten P, Lohr T, Sanchez Milde L, von Krosigk N, Docking TR, Heuser M, Karsan A, Humphries RK. Lai CK, et al. Blood Cancer J. 2017 Sep 29;7(9):e613. doi: 10.1038/bcj.2017.86. Blood Cancer J. 2017. PMID: 28960191 Free PMC article.
The methyltransferase G9a regulates HoxA9-dependent transcription in AML.
Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, Humphries RK, Rossi FM. Lehnertz B, et al. Genes Dev. 2014 Feb 15;28(4):317-27. doi: 10.1101/gad.236794.113. Genes Dev. 2014. PMID: 24532712 Free PMC article.
28 results