Rokosz LL - Search Results

1

Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.

Guo T, Shao Y, Qian G, Rokosz LL, Stauffer TM, Hunter RC, Babu SD, Gu H, Hobbs DW. Guo T, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3696-700. doi: 10.1016/j.bmcl.2005.05.085. Bioorg Med Chem Lett. 2005. PMID: 15978811

2

Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis.

Guo T, Hunter RC, Gu H, Rokosz LL, Stauffer TM, Hobbs DW. Guo T, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3691-5. doi: 10.1016/j.bmcl.2005.05.039. Bioorg Med Chem Lett. 2005. PMID: 15953726

3

Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.

Rokosz LL, Huang CY, Reader JC, Stauffer TM, Chelsky D, Sigal NH, Ganguly AK, Baldwin JJ. Rokosz LL, et al. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5537-43. doi: 10.1016/j.bmcl.2005.08.074. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16202593

4

Guiding farnesyltransferase inhibitors from an ECLiPS library to the catalytic zinc.

Huang CY, Stauffer TM, Strickland CL, Reader JC, Huang H, Li G, Cooper AB, Doll RJ, Ganguly AK, Baldwin JJ, Rokosz LL. Huang CY, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2006 Feb;16(3):507-11. doi: 10.1016/j.bmcl.2005.10.070. Epub 2005 Nov 10. Bioorg Med Chem Lett. 2006. PMID: 16289818

5

Synthesis and structure-activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists.

Merritt JR, Rokosz LL, Nelson KH Jr, Kaiser B, Wang W, Stauffer TM, Ozgur LE, Schilling A, Li G, Baldwin JJ, Taveras AG, Dwyer MP, Chao J. Merritt JR, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4107-10. doi: 10.1016/j.bmcl.2006.04.082. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16697193

6

Discovery and preliminary evaluation of 5-(4-phenylbenzyl)oxazole-4-carboxamides as prostacyclin receptor antagonists.

Brescia MR, Rokosz LL, Cole AG, Stauffer TM, Lehrach JM, Auld DS, Henderson I, Webb ML. Brescia MR, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1211-5. doi: 10.1016/j.bmcl.2006.12.025. Epub 2006 Dec 12. Bioorg Med Chem Lett. 2007. PMID: 17239589

7

Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists.

Guo T, Gu H, Hobbs DW, Busler DE, Rokosz LL. Guo T, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1718-21. doi: 10.1016/j.bmcl.2006.12.080. Epub 2006 Dec 24. Bioorg Med Chem Lett. 2007. PMID: 17251014

8

Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as gamma-secretase inhibitors.

Guo T, Gu H, Hobbs DW, Rokosz LL, Stauffer TM, Jacob B, Clader JW. Guo T, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3010-3. doi: 10.1016/j.bmcl.2007.03.055. Epub 2007 Mar 23. Bioorg Med Chem Lett. 2007. PMID: 17418571

9

Synthesis and structure-activity relationships of new disubstituted phenyl-containing 3,4-diamino-3-cyclobutene-1,2-diones as CXCR2 receptor antagonists.

Lai G, Merritt JR, He Z, Feng D, Chao J, Czarniecki MF, Rokosz LL, Stauffer TM, Rindgen D, Taveras AG. Lai G, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1864-8. doi: 10.1016/j.bmcl.2008.02.010. Epub 2008 Feb 10. Bioorg Med Chem Lett. 2008. PMID: 18304809

10

Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A(2A) receptor antagonists.

Cole AG, Stauffer TM, Rokosz LL, Metzger A, Dillard LW, Zeng W, Henderson I. Cole AG, et al. Among authors: rokosz ll. Bioorg Med Chem Lett. 2009 Jan 15;19(2):378-81. doi: 10.1016/j.bmcl.2008.11.066. Epub 2008 Nov 24. Bioorg Med Chem Lett. 2009. PMID: 19059776

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