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Page 1
Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine.
Ray AS, Hernandez-Santiago BI, Mathew JS, Murakami E, Bozeman C, Xie MY, Dutschman GE, Gullen E, Yang Z, Hurwitz S, Cheng YC, Chu CK, McClure H, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: gullen e. Antimicrob Agents Chemother. 2005 May;49(5):1994-2001. doi: 10.1128/AAC.49.5.1994-2001.2005. Antimicrob Agents Chemother. 2005. PMID: 15855524 Free PMC article.
Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.
Dutschman GE, Bridges EG, Liu SH, Gullen E, Guo X, Kukhanova M, Cheng YC. Dutschman GE, et al. Among authors: gullen e. Antimicrob Agents Chemother. 1998 Jul;42(7):1799-804. doi: 10.1128/AAC.42.7.1799. Antimicrob Agents Chemother. 1998. PMID: 9661024 Free PMC article.
Synthesis and antiviral activity of helioxanthin analogues.
Yeo H, Li Y, Fu L, Zhu JL, Gullen EA, Dutschman GE, Lee Y, Chung R, Huang ES, Austin DJ, Cheng YC. Yeo H, et al. Among authors: gullen ea. J Med Chem. 2005 Jan 27;48(2):534-46. doi: 10.1021/jm034265a. J Med Chem. 2005. PMID: 15658867
Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.
Liu MC, Luo MZ, Mozdziesz DE, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC. Liu MC, et al. Among authors: gullen ea. Nucleosides Nucleotides Nucleic Acids. 2005;24(2):135-45. doi: 10.1081/NCN-51898. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15822619
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitro.
Cheng Y, Tsou LK, Cai J, Aya T, Dutschman GE, Gullen EA, Grill SP, Chen AP, Lindenbach BD, Hamilton AD, Cheng YC. Cheng Y, et al. Among authors: gullen ea. Antimicrob Agents Chemother. 2010 Jan;54(1):197-206. doi: 10.1128/AAC.01206-09. Epub 2009 Nov 9. Antimicrob Agents Chemother. 2010. PMID: 19901090 Free PMC article.
Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro.
Lin TS, Luo MZ, Liu MC, Zhu YL, Gullen E, Dutschman GE, Cheng YC. Lin TS, et al. Among authors: gullen e. J Med Chem. 1996 Apr 26;39(9):1757-9. doi: 10.1021/jm950836q. J Med Chem. 1996. PMID: 8627596 No abstract available.
51 results