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A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Kochi Y, Yamada R, Suzuki A, Harley JB, Shirasawa S, Sawada T, Bae SC, Tokuhiro S, Chang X, Sekine A, Takahashi A, Tsunoda T, Ohnishi Y, Kaufman KM, Kang CP, Kang C, Otsubo S, Yumura W, Mimori A, Koike T, Nakamura Y, Sasazuki T, Yamamoto K. Kochi Y, et al. Among authors: nakamura y. Nat Genet. 2005 May;37(5):478-85. doi: 10.1038/ng1540. Epub 2005 Apr 17. Nat Genet. 2005. PMID: 15838509 Free PMC article.
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, Ohtsuki M, Furukawa H, Yoshino S, Yukioka M, Tohma S, Matsubara T, Wakitani S, Teshima R, Nishioka Y, Sekine A, Iida A, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K. Suzuki A, et al. Among authors: nakamura y. Nat Genet. 2003 Aug;34(4):395-402. doi: 10.1038/ng1206. Nat Genet. 2003. PMID: 12833157
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Tokuhiro S, Yamada R, Chang X, Suzuki A, Kochi Y, Sawada T, Suzuki M, Nagasaki M, Ohtsuki M, Ono M, Furukawa H, Nagashima M, Yoshino S, Mabuchi A, Sekine A, Saito S, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K. Tokuhiro S, et al. Among authors: nakamura y. Nat Genet. 2003 Dec;35(4):341-8. doi: 10.1038/ng1267. Epub 2003 Nov 9. Nat Genet. 2003. PMID: 14608356
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
Kochi Y, Yamada R, Kobayashi K, Takahashi A, Suzuki A, Sekine A, Mabuchi A, Akiyama F, Tsunoda T, Nakamura Y, Yamamoto K. Kochi Y, et al. Among authors: nakamura y. Arthritis Rheum. 2004 Jan;50(1):63-71. doi: 10.1002/art.11366. Arthritis Rheum. 2004. PMID: 14730600 Free article.
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
Suzuki A, Yamada R, Kochi Y, Sawada T, Okada Y, Matsuda K, Kamatani Y, Mori M, Shimane K, Hirabayashi Y, Takahashi A, Tsunoda T, Miyatake A, Kubo M, Kamatani N, Nakamura Y, Yamamoto K. Suzuki A, et al. Among authors: nakamura y. Nat Genet. 2008 Oct;40(10):1224-9. doi: 10.1038/ng.205. Epub 2008 Sep 14. Nat Genet. 2008. PMID: 18794858
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, Yamazaki K, Hosono N, Myouzen K, Tsunoda T, Kamatani N, Furuichi T, Ikegawa S, Ohmura K, Mimori T, Matsuda F, Iwamoto T, Momohara S, Yamanaka H, Yamada R, Kubo M, Nakamura Y, Yamamoto K. Kochi Y, et al. Among authors: nakamura y. Nat Genet. 2010 Jun;42(6):515-9. doi: 10.1038/ng.583. Epub 2010 May 9. Nat Genet. 2010. PMID: 20453841
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K. Okada Y, et al. Among authors: nakamura y. Nat Genet. 2012 Mar 25;44(5):511-6. doi: 10.1038/ng.2231. Nat Genet. 2012. PMID: 22446963
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