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Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas.
Pfister S, Remke M, Toedt G, Werft W, Benner A, Mendrzyk F, Wittmann A, Devens F, von Hoff K, Rutkowski S, Kulozik A, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A. Pfister S, et al. Among authors: mendrzyk f. Genes Chromosomes Cancer. 2007 Sep;46(9):839-51. doi: 10.1002/gcc.20471. Genes Chromosomes Cancer. 2007. PMID: 17592618
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci.
Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, Wittmann A, Devens F, Gerber NU, Joos S, Kulozik A, Reifenberger G, Rutkowski S, Wiestler OD, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A. Pfister S, et al. Among authors: mendrzyk f. J Clin Oncol. 2009 Apr 1;27(10):1627-36. doi: 10.1200/JCO.2008.17.9432. Epub 2009 Mar 2. J Clin Oncol. 2009. PMID: 19255330
Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma.
Pfister S, Schlaeger C, Mendrzyk F, Wittmann A, Benner A, Kulozik A, Scheurlen W, Radlwimmer B, Lichter P. Pfister S, et al. Among authors: mendrzyk f. Nucleic Acids Res. 2007;35(7):e51. doi: 10.1093/nar/gkm094. Epub 2007 Mar 7. Nucleic Acids Res. 2007. PMID: 17344319 Free PMC article.