Cloarec O - Search Results

1

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

Cloarec O, Dumas ME, Craig A, Barton RH, Trygg J, Hudson J, Blancher C, Gauguier D, Lindon JC, Holmes E, Nicholson J. Cloarec O, et al. Anal Chem. 2005 Mar 1;77(5):1282-9. doi: 10.1021/ac048630x. Anal Chem. 2005. PMID: 15732908

2

Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl2 toxicity.

Holmes E, Cloarec O, Nicholson JK. Holmes E, et al. Among authors: cloarec o. J Proteome Res. 2006 Jun;5(6):1313-20. doi: 10.1021/pr050399w. J Proteome Res. 2006. PMID: 16739983

3

Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies.

Cloarec O, Dumas ME, Trygg J, Craig A, Barton RH, Lindon JC, Nicholson JK, Holmes E. Cloarec O, et al. Anal Chem. 2005 Jan 15;77(2):517-26. doi: 10.1021/ac048803i. Anal Chem. 2005. PMID: 15649048

4

Scaling and normalization effects in NMR spectroscopic metabonomic data sets.

Craig A, Cloarec O, Holmes E, Nicholson JK, Lindon JC. Craig A, et al. Among authors: cloarec o. Anal Chem. 2006 Apr 1;78(7):2262-7. doi: 10.1021/ac0519312. Anal Chem. 2006. PMID: 16579606

5

Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis.

Crockford DJ, Lindon JC, Cloarec O, Plumb RS, Bruce SJ, Zirah S, Rainville P, Stumpf CL, Johnson K, Holmes E, Nicholson JK. Crockford DJ, et al. Among authors: cloarec o. Anal Chem. 2006 Jul 1;78(13):4398-408. doi: 10.1021/ac060168o. Anal Chem. 2006. PMID: 16808447

6

Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy.

Holmes E, Loo RL, Cloarec O, Coen M, Tang H, Maibaum E, Bruce S, Chan Q, Elliott P, Stamler J, Wilson ID, Lindon JC, Nicholson JK. Holmes E, et al. Among authors: cloarec o. Anal Chem. 2007 Apr 1;79(7):2629-40. doi: 10.1021/ac062305n. Epub 2007 Feb 27. Anal Chem. 2007. PMID: 17323917 Free PMC article.

7

Virtual chromatographic resolution enhancement in cryoflow LC-NMR experiments via statistical total correlation spectroscopy.

Cloarec O, Campbell A, Tseng LH, Braumann U, Spraul M, Scarfe G, Weaver R, Nicholson JK. Cloarec O, et al. Anal Chem. 2007 May 1;79(9):3304-11. doi: 10.1021/ac061928y. Epub 2007 Mar 30. Anal Chem. 2007. PMID: 17394288

8

Statistical correlation and projection methods for improved information recovery from diffusion-edited NMR spectra of biological samples.

Smith LM, Maher AD, Cloarec O, Rantalainen M, Tang H, Elliott P, Stamler J, Lindon JC, Holmes E, Nicholson JK. Smith LM, et al. Among authors: cloarec o. Anal Chem. 2007 Aug 1;79(15):5682-9. doi: 10.1021/ac0703754. Epub 2007 Jun 23. Anal Chem. 2007. PMID: 17585837

9

Heteronuclear 1H-31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity.

Coen M, Hong YS, Cloarec O, Rhode CM, Reily MD, Robertson DG, Holmes E, Lindon JC, Nicholson JK. Coen M, et al. Among authors: cloarec o. Anal Chem. 2007 Dec 1;79(23):8956-66. doi: 10.1021/ac0713961. Epub 2007 Nov 1. Anal Chem. 2007. PMID: 17973499

10

Magic angle spinning NMR and 1H-31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies.

Wang Y, Cloarec O, Tang H, Lindon JC, Holmes E, Kochhar S, Nicholson JK. Wang Y, et al. Among authors: cloarec o. Anal Chem. 2008 Feb 15;80(4):1058-66. doi: 10.1021/ac701988a. Epub 2008 Jan 19. Anal Chem. 2008. PMID: 18205334

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