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A small molecule-kinase interaction map for clinical kinase inhibitors.
Fabian MA, Biggs WH 3rd, Treiber DK, Atteridge CE, Azimioara MD, Benedetti MG, Carter TA, Ciceri P, Edeen PT, Floyd M, Ford JM, Galvin M, Gerlach JL, Grotzfeld RM, Herrgard S, Insko DE, Insko MA, Lai AG, Lélias JM, Mehta SA, Milanov ZV, Velasco AM, Wodicka LM, Patel HK, Zarrinkar PP, Lockhart DJ. Fabian MA, et al. Among authors: lockhart dj. Nat Biotechnol. 2005 Mar;23(3):329-36. doi: 10.1038/nbt1068. Epub 2005 Feb 13. Nat Biotechnol. 2005. PMID: 15711537 Free article.
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.
Carter TA, Wodicka LM, Shah NP, Velasco AM, Fabian MA, Treiber DK, Milanov ZV, Atteridge CE, Biggs WH 3rd, Edeen PT, Floyd M, Ford JM, Grotzfeld RM, Herrgard S, Insko DE, Mehta SA, Patel HK, Pao W, Sawyers CL, Varmus H, Zarrinkar PP, Lockhart DJ. Carter TA, et al. Among authors: lockhart dj. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11011-6. doi: 10.1073/pnas.0504952102. Epub 2005 Jul 26. Proc Natl Acad Sci U S A. 2005. PMID: 16046538 Free PMC article.
Arylcarboxyamino-substituted diaryl ureas as potent and selective FLT3 inhibitors.
Patel HK, Grotzfeld RM, Lai AG, Mehta SA, Milanov ZV, Chao Q, Sprankle KG, Carter TA, Velasco AM, Fabian MA, James J, Treiber DK, Lockhart DJ, Zarrinkar PP, Bhagwat SS. Patel HK, et al. Among authors: lockhart dj. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5182-5. doi: 10.1016/j.bmcl.2009.07.024. Epub 2009 Jul 9. Bioorg Med Chem Lett. 2009. PMID: 19646870
Tuning a three-component reaction for trapping kinase substrate complexes.
Statsuk AV, Maly DJ, Seeliger MA, Fabian MA, Biggs WH 3rd, Lockhart DJ, Zarrinkar PP, Kuriyan J, Shokat KM. Statsuk AV, et al. Among authors: lockhart dj. J Am Chem Soc. 2008 Dec 24;130(51):17568-74. doi: 10.1021/ja807066f. J Am Chem Soc. 2008. PMID: 19053485 Free PMC article.
Parallel identification of new genes in Saccharomyces cerevisiae.
Oshiro G, Wodicka LM, Washburn MP, Yates JR 3rd, Lockhart DJ, Winzeler EA. Oshiro G, et al. Among authors: lockhart dj. Genome Res. 2002 Aug;12(8):1210-20. doi: 10.1101/gr.226802. Genome Res. 2002. PMID: 12176929 Free PMC article.
Arrays of arrays for high-throughput gene expression profiling.
Zarrinkar PP, Mainquist JK, Zamora M, Stern D, Welsh JB, Sapinoso LM, Hampton GM, Lockhart DJ. Zarrinkar PP, et al. Among authors: lockhart dj. Genome Res. 2001 Jul;11(7):1256-61. doi: 10.1101/gr.gr-1748r. Genome Res. 2001. PMID: 11435408 Free PMC article.
72 results