Xuong NH - Search Results

1

Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA.

Kim C, Xuong NH, Taylor SS. Kim C, et al. Among authors: xuong nh. Science. 2005 Feb 4;307(5710):690-6. doi: 10.1126/science.1104607. Science. 2005. PMID: 15692043

2

Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism.

Yang J, Ten Eyck LF, Xuong NH, Taylor SS. Yang J, et al. Among authors: xuong nh. J Mol Biol. 2004 Feb 13;336(2):473-87. doi: 10.1016/j.jmb.2003.11.044. J Mol Biol. 2004. PMID: 14757059

3

Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase.

Madhusudan, Akamine P, Xuong NH, Taylor SS. Madhusudan, et al. Among authors: xuong nh. Nat Struct Biol. 2002 Apr;9(4):273-7. doi: 10.1038/nsb780. Nat Struct Biol. 2002. PMID: 11896404

4

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure.

Akamine P, Madhusudan, Wu J, Xuong NH, Ten Eyck LF, Taylor SS. Akamine P, et al. Among authors: xuong nh. J Mol Biol. 2003 Mar 14;327(1):159-71. doi: 10.1016/s0022-2836(02)01446-8. J Mol Biol. 2003. PMID: 12614615

5

Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit.

Akamine P, Madhusudan, Brunton LL, Ou HD, Canaves JM, Xuong NH, Taylor SS. Akamine P, et al. Among authors: xuong nh. Biochemistry. 2004 Jan 13;43(1):85-96. doi: 10.1021/bi035042p. Biochemistry. 2004. PMID: 14705934

6

RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.

Wu J, Brown S, Xuong NH, Taylor SS. Wu J, et al. Among authors: xuong nh. Structure. 2004 Jun;12(6):1057-65. doi: 10.1016/j.str.2004.03.022. Structure. 2004. PMID: 15274925 Free article.

7

Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.

Wu J, Yang J, Kannan N, Madhusudan, Xuong NH, Ten Eyck LF, Taylor SS. Wu J, et al. Among authors: xuong nh. Protein Sci. 2005 Nov;14(11):2871-9. doi: 10.1110/ps.051715205. Protein Sci. 2005. PMID: 16253959 Free PMC article.

8

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase.

Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS. Kinderman FS, et al. Among authors: xuong nh. Mol Cell. 2006 Nov 3;24(3):397-408. doi: 10.1016/j.molcel.2006.09.015. Mol Cell. 2006. PMID: 17081990 Free PMC article.

9

Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.

Narayana N, Cox S, Shaltiel S, Taylor SS, Xuong N. Narayana N, et al. Biochemistry. 1997 Apr 15;36(15):4438-48. doi: 10.1021/bi961947+. Biochemistry. 1997. PMID: 9109651

10

Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.

Narayana N, Diller TC, Koide K, Bunnage ME, Nicolaou KC, Brunton LL, Xuong NH, Ten Eyck LF, Taylor SS. Narayana N, et al. Among authors: xuong nh. Biochemistry. 1999 Feb 23;38(8):2367-76. doi: 10.1021/bi9820659. Biochemistry. 1999. PMID: 10029530

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