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Page 1
Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study.
Cook LJ, Ho LW, Wang L, Terrenoire E, Brayne C, Evans JG, Xuereb J, Cairns NJ, Turic D, Hollingworth P, Moore PJ, Jehu L, Archer N, Walter S, Foy C, Edmondson A, Powell J, Lovestone S, Williams J, Rubinsztein DC. Cook LJ, et al. Among authors: brayne c. Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132B(1):5-8. doi: 10.1002/ajmg.b.30068. Am J Med Genet B Neuropsychiatr Genet. 2005. PMID: 15690550
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Cook LJ, Ho LW, Taylor AE, Brayne C, Evans JG, Xuereb J, Cairns NJ, Pritchard A, Lemmon H, Mann D, St Clair D, Turic D, Hollingworth P, Moore PJ, Jehu L, Archer N, Walter S, Foy C, Edmondson A, Powell J, Lovestone S, Owen MJ, Williams J, Lendon C, Rubinsztein DC. Cook LJ, et al. Among authors: brayne c. Neurosci Lett. 2004 Mar 25;358(2):142-6. doi: 10.1016/j.neulet.2004.01.016. Neurosci Lett. 2004. PMID: 15026168
DAPK1 variants are associated with Alzheimer's disease and allele-specific expression.
Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JS, Smemo S, Hinrichs A, Tacey K, Toombs TA, Kwok S, Catanese J, White TJ, Maxwell TJ, Hollingworth P, Abraham R, Rubinsztein DC, Brayne C, Wavrant-De Vrièze F, Hardy J, O'Donovan M, Lovestone S, Morris JC, Thal LJ, Owen M, Williams J, Goate A. Li Y, et al. Among authors: brayne c. Hum Mol Genet. 2006 Sep 1;15(17):2560-8. doi: 10.1093/hmg/ddl178. Epub 2006 Jul 17. Hum Mol Genet. 2006. PMID: 16847012
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.
Grupe A, Abraham R, Li Y, Rowland C, Hollingworth P, Morgan A, Jehu L, Segurado R, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, Brayne C, Rubinsztein D, Gill M, Lawlor B, Lovestone S, Holmans P, O'Donovan M, Morris JC, Thal L, Goate A, Owen MJ, Williams J. Grupe A, et al. Among authors: brayne c. Hum Mol Genet. 2007 Apr 15;16(8):865-73. doi: 10.1093/hmg/ddm031. Epub 2007 Feb 22. Hum Mol Genet. 2007. PMID: 17317784
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, Perlmutter JS, O'Donovan MC, Morris JC, Brayne C, Rubinsztein DC, Lovestone S, Thal LJ, Owen MJ, Williams J. Li Y, et al. Among authors: brayne c. Hum Mol Genet. 2008 Mar 1;17(5):759-67. doi: 10.1093/hmg/ddm348. Epub 2007 Dec 6. Hum Mol Genet. 2008. PMID: 18063669
Education, occupation and retirement age effects on the age of onset of Alzheimer's disease.
Lupton MK, Stahl D, Archer N, Foy C, Poppe M, Lovestone S, Hollingworth P, Williams J, Owen MJ, Dowzell K, Abraham R, Sims R, Brayne C, Rubinsztein D, Gill M, Lawlor B, Lynch A, Powell JF. Lupton MK, et al. Among authors: brayne c. Int J Geriatr Psychiatry. 2010 Jan;25(1):30-6. doi: 10.1002/gps.2294. Int J Geriatr Psychiatry. 2010. PMID: 19459177
855 results