Desta Z - Search Results

1

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.

Jin Y, Desta Z, Stearns V, Ward B, Ho H, Lee KH, Skaar T, Storniolo AM, Li L, Araba A, Blanchard R, Nguyen A, Ullmer L, Hayden J, Lemler S, Weinshilboum RM, Rae JM, Hayes DF, Flockhart DA. Jin Y, et al. Among authors: desta z. J Natl Cancer Inst. 2005 Jan 5;97(1):30-9. doi: 10.1093/jnci/dji005. J Natl Cancer Inst. 2005. PMID: 15632378

2

The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6.

Desta Z, Wu GM, Morocho AM, Flockhart DA. Desta Z, et al. Drug Metab Dispos. 2002 Mar;30(3):336-43. doi: 10.1124/dmd.30.3.336. Drug Metab Dispos. 2002. PMID: 11854155

3

In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin.

Desta Z, Soukhova N, Flockhart DA. Desta Z, et al. J Clin Psychopharmacol. 2002 Apr;22(2):162-8. doi: 10.1097/00004714-200204000-00009. J Clin Psychopharmacol. 2002. PMID: 11910261

4

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.

Rae JM, Soukhova NV, Flockhart DA, Desta Z. Rae JM, et al. Among authors: desta z. Drug Metab Dispos. 2002 May;30(5):525-30. doi: 10.1124/dmd.30.5.525. Drug Metab Dispos. 2002. PMID: 11950782

5

Clinical significance of the cytochrome P450 2C19 genetic polymorphism.

Desta Z, Zhao X, Shin JG, Flockhart DA. Desta Z, et al. Clin Pharmacokinet. 2002;41(12):913-58. doi: 10.2165/00003088-200241120-00002. Clin Pharmacokinet. 2002. PMID: 12222994 Review.

6

Sequence diversity and functional characterization of the 5'-regulatory region of human CYP2C19.

Arefayene M, Skaar TC, Zhao X, Rae JM, Tanus-Santos JE, Brinkmann U, Brehm I, Salat U, Nguyen A, Desta Z, Flockhart DA. Arefayene M, et al. Among authors: desta z. Pharmacogenetics. 2003 Apr;13(4):199-206. doi: 10.1097/00008571-200304000-00004. Pharmacogenetics. 2003. PMID: 12668916

7

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity.

Ward BA, Gorski JC, Jones DR, Hall SD, Flockhart DA, Desta Z. Ward BA, et al. Among authors: desta z. J Pharmacol Exp Ther. 2003 Jul;306(1):287-300. doi: 10.1124/jpet.103.049601. Epub 2003 Apr 3. J Pharmacol Exp Ther. 2003. PMID: 12676886

8

Quantification of tamoxifen and three metabolites in plasma by high-performance liquid chromatography with fluorescence detection: application to a clinical trial.

Lee KH, Ward BA, Desta Z, Flockhart DA, Jones DR. Lee KH, et al. Among authors: desta z. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 5;791(1-2):245-53. doi: 10.1016/s1570-0232(03)00218-6. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12798184

9

Variability of heart rate correction methods for the QT interval.

Desai M, Li L, Desta Z, Malik M, Flockhart D. Desai M, et al. Among authors: desta z. Br J Clin Pharmacol. 2003 Jun;55(6):511-7. doi: 10.1046/j.1365-2125.2003.01791.x. Br J Clin Pharmacol. 2003. PMID: 12814443 Free PMC article. Clinical Trial.

10

Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine.

Stearns V, Johnson MD, Rae JM, Morocho A, Novielli A, Bhargava P, Hayes DF, Desta Z, Flockhart DA. Stearns V, et al. Among authors: desta z. J Natl Cancer Inst. 2003 Dec 3;95(23):1758-64. doi: 10.1093/jnci/djg108. J Natl Cancer Inst. 2003. PMID: 14652237 Clinical Trial.

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