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Eleven novel single nucleotide polymorphisms in the NR1I2 (PXR) gene, four of which induce non-synonymous amino acid alterations.
Koyano S, Kurose K, Ozawa S, Saeki M, Nakajima Y, Hasegawa R, Komamura K, Ueno K, Kamakura S, Nakajima T, Saito H, Kimura H, Goto Y, Saitoh O, Katoh M, Ohnuma T, Kawai M, Sugai K, Ohtsuki T, Suzuki C, Minami N, Saito Y, Sawada J. Koyano S, et al. Among authors: nakajima t, nakajima y. Drug Metab Pharmacokinet. 2002;17(6):561-5. doi: 10.2133/dmpk.17.561. Drug Metab Pharmacokinet. 2002. PMID: 15618712 Free article.
Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.
Murayama N, Soyama A, Saito Y, Nakajima Y, Komamura K, Ueno K, Kamakura S, Kitakaze M, Kimura H, Goto Y, Saitoh O, Katoh M, Ohnuma T, Kawai M, Sugai K, Ohtsuki T, Suzuki C, Minami N, Ozawa S, Sawada J. Murayama N, et al. Among authors: nakajima y. J Pharmacol Exp Ther. 2004 Jan;308(1):300-6. doi: 10.1124/jpet.103.055798. Epub 2003 Oct 16. J Pharmacol Exp Ther. 2004. PMID: 14563787
Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.
Nakajima Y, Saito Y, Shiseki K, Fukushima-Uesaka H, Hasegawa R, Ozawa S, Sugai K, Katoh M, Saitoh O, Ohnuma T, Kawai M, Ohtsuki T, Suzuki C, Minami N, Kimura H, Goto Y, Kamatani N, Kaniwa N, Sawada J. Nakajima Y, et al. Eur J Clin Pharmacol. 2005 Mar;61(1):25-34. doi: 10.1007/s00228-004-0878-1. Epub 2005 Feb 4. Eur J Clin Pharmacol. 2005. PMID: 15692831 Clinical Trial.
CYP2C8 haplotype structures and their influence on pharmacokinetics of paclitaxel in a Japanese population.
Saito Y, Katori N, Soyama A, Nakajima Y, Yoshitani T, Kim SR, Fukushima-Uesaka H, Kurose K, Kaniwa N, Ozawa S, Kamatani N, Komamura K, Kamakura S, Kitakaze M, Tomoike H, Sugai K, Minami N, Kimura H, Goto Y, Minami H, Yoshida T, Kunitoh H, Ohe Y, Yamamoto N, Tamura T, Saijo N, Sawada J. Saito Y, et al. Among authors: nakajima y. Pharmacogenet Genomics. 2007 Jul;17(7):461-71. doi: 10.1097/FPC.0b013e32805b72c1. Pharmacogenet Genomics. 2007. PMID: 17558302
Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
Yawata A, Kim SR, Miyajima A, Kubo T, Ishida S, Saito Y, Nakajima Y, Katori N, Matsumoto Y, Fukuoka M, Ohno Y, Ozawa S, Sawada J. Yawata A, et al. Among authors: nakajima y. Cancer Chemother Pharmacol. 2005 Nov;56(5):465-72. doi: 10.1007/s00280-005-1018-z. Epub 2005 May 26. Cancer Chemother Pharmacol. 2005. PMID: 15918040
Impact of the haplotype CYP3A4*16B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer.
Nakajima Y, Yoshitani T, Fukushima-Uesaka H, Saito Y, Kaniwa N, Kurose K, Ozawa S, Aoyagi N, Kamatani N, Yamamoto N, Kunitoh H, Ohe Y, Tamura T, Yoshida T, Minami H, Saijo N, Katori N, Sawada J. Nakajima Y, et al. Clin Pharmacol Ther. 2006 Aug;80(2):179-91. doi: 10.1016/j.clpt.2006.04.012. Epub 2006 Jul 3. Clin Pharmacol Ther. 2006. PMID: 16890579
Impact of bone marrow nucleated cell subfractions on transplant outcomes in patients with acute lymphoblastic leukemia.
Nukui J, Tachibana T, Miyazaki T, Tanaka M, Matsumoto K, Ishii Y, Numata A, Nakajima Y, Matsumura A, Suzuki T, Izumi A, Hirose N, Yamamoto K, Hagihara M, Fujisawa S, Nakajima H. Nukui J, et al. Among authors: nakajima y. Hematology. 2024 Dec;29(1):2424053. doi: 10.1080/16078454.2024.2424053. Epub 2024 Nov 4. Hematology. 2024. PMID: 39495151
3,667 results