Worgall S - Search Results

1

Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis.

Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D, Dinner M, Wisniewski K, Kaplitt M, Greenwald BM, Howell JD, Strybing K, Dyke J, Voss H. Crystal RG, et al. Among authors: worgall s. Hum Gene Ther. 2004 Nov;15(11):1131-54. doi: 10.1089/hum.2004.15.1131. Hum Gene Ther. 2004. PMID: 15610613 Clinical Trial.

2

Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ.

Wolff G, Worgall S, van Rooijen N, Song WR, Harvey BG, Crystal RG. Wolff G, et al. Among authors: worgall s. J Virol. 1997 Jan;71(1):624-9. doi: 10.1128/JVI.71.1.624-629.1997. J Virol. 1997. PMID: 8985392 Free PMC article.

3

Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Worgall S, et al. Hum Gene Ther. 1997 Jan 1;8(1):37-44. doi: 10.1089/hum.1997.8.1-37. Hum Gene Ther. 1997. PMID: 8989993

4

Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract.

Worgall S, Leopold PL, Wolff G, Ferris B, Van Roijen N, Crystal RG. Worgall S, et al. Hum Gene Ther. 1997 Sep 20;8(14):1675-84. doi: 10.1089/hum.1997.8.14-1675. Hum Gene Ther. 1997. PMID: 9322870

5

Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells.

Leopold PL, Ferris B, Grinberg I, Worgall S, Hackett NR, Crystal RG. Leopold PL, et al. Among authors: worgall s. Hum Gene Ther. 1998 Feb 10;9(3):367-78. doi: 10.1089/hum.1998.9.3-367. Hum Gene Ther. 1998. PMID: 9508054

6

Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma.

Topf N, Worgall S, Hackett NR, Crystal RG. Topf N, et al. Among authors: worgall s. Gene Ther. 1998 Apr;5(4):507-13. doi: 10.1038/sj.gt.3300611. Gene Ther. 1998. PMID: 9614575

7

Selective expansion of alveolar macrophages in vivo by adenovirus-mediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA.

Worgall S, Singh R, Leopold PL, Kaner RJ, Hackett NR, Topf N, Moore MA, Crystal RG. Worgall S, et al. Blood. 1999 Jan 15;93(2):655-66. Blood. 1999. PMID: 9885228 Free article.

8

Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.

Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J, Finberg R, Falck-Pedersen E, Crystal RG. Kaner RJ, et al. Among authors: worgall s. Am J Respir Cell Mol Biol. 1999 Mar;20(3):361-70. doi: 10.1165/ajrcmb.20.3.3398. Am J Respir Cell Mol Biol. 1999. PMID: 10030833

9

E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells.

Ramalingam R, Rafii S, Worgall S, Brough DE, Crystal RG. Ramalingam R, et al. Among authors: worgall s. Blood. 1999 May 1;93(9):2936-44. Blood. 1999. PMID: 10216088 Free article.

10

Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages.

Worgall S, Connor R, Kaner RJ, Fenamore E, Sheridan K, Singh R, Crystal RG. Worgall S, et al. J Virol. 1999 Jul;73(7):5865-74. doi: 10.1128/JVI.73.7.5865-5874.1999. J Virol. 1999. PMID: 10364338 Free PMC article.

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