Rath VL - Search Results

1

5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.

Wright SW, Rath VL, Genereux PE, Hageman DL, Levy CB, McClure LD, McCoid SC, McPherson RK, Schelhorn TM, Wilder DE, Zavadoski WJ, Gibbs EM, Treadway JL. Wright SW, et al. Among authors: rath vl. Bioorg Med Chem Lett. 2005 Jan 17;15(2):459-65. doi: 10.1016/j.bmcl.2004.10.048. Bioorg Med Chem Lett. 2005. PMID: 15603973

2

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL. Ekstrom JL, et al. Among authors: rath vl. Chem Biol. 2002 Aug;9(8):915-24. doi: 10.1016/s1074-5521(02)00186-2. Chem Biol. 2002. PMID: 12204691

3

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ. Rath VL, et al. Chem Biol. 2000 Sep;7(9):677-82. doi: 10.1016/s1074-5521(00)00004-1. Chem Biol. 2000. PMID: 10980448

4

Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors.

Ercan-Fang N, Taylor MR, Treadway JL, Levy CB, Genereux PE, Gibbs EM, Rath VL, Kwon Y, Gannon MC, Nuttall FQ. Ercan-Fang N, et al. Among authors: rath vl. Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E366-72. doi: 10.1152/ajpendo.00264.2004. Epub 2005 Mar 29. Am J Physiol Endocrinol Metab. 2005. PMID: 15797986 Free article.

5

Integrated effects of multiple modulators on human liver glycogen phosphorylase a.

Ercan-Fang N, Gannon MC, Rath VL, Treadway JL, Taylor MR, Nuttall FQ. Ercan-Fang N, et al. Among authors: rath vl. Am J Physiol Endocrinol Metab. 2002 Jul;283(1):E29-37. doi: 10.1152/ajpendo.00425.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 12067839 Free article.

6

Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.

Rath VL, Ammirati M, LeMotte PK, Fennell KF, Mansour MN, Danley DE, Hynes TR, Schulte GK, Wasilko DJ, Pandit J. Rath VL, et al. Mol Cell. 2000 Jul;6(1):139-48. Mol Cell. 2000. PMID: 10949035 Free article.

7

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.

Pauly TA, Ekstrom JL, Beebe DA, Chrunyk B, Cunningham D, Griffor M, Kamath A, Lee SE, Madura R, Mcguire D, Subashi T, Wasilko D, Watts P, Mylari BL, Oates PJ, Adams PD, Rath VL. Pauly TA, et al. Among authors: rath vl. Structure. 2003 Sep;11(9):1071-85. doi: 10.1016/s0969-2126(03)00167-9. Structure. 2003. PMID: 12962626 Free article.

8

Specificity determinants of human cathepsin s revealed by crystal structures of complexes.

Pauly TA, Sulea T, Ammirati M, Sivaraman J, Danley DE, Griffor MC, Kamath AV, Wang IK, Laird ER, Seddon AP, Ménard R, Cygler M, Rath VL. Pauly TA, et al. Among authors: rath vl. Biochemistry. 2003 Mar 25;42(11):3203-13. doi: 10.1021/bi027308i. Biochemistry. 2003. PMID: 12641451

9

The evolution of an allosteric site in phosphorylase.

Rath VL, Lin K, Hwang PK, Fletterick RJ. Rath VL, et al. Structure. 1996 Apr 15;4(4):463-73. doi: 10.1016/s0969-2126(96)00051-2. Structure. 1996. PMID: 8740368 Free article.

10

Purification and crystallization of glycogen phosphorylase from Saccharomyces cerevisiae.

Rath VL, Hwang PK, Fletterick RJ. Rath VL, et al. J Mol Biol. 1992 Jun 20;225(4):1027-34. doi: 10.1016/0022-2836(92)90102-p. J Mol Biol. 1992. PMID: 1613787

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