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Page 1
Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.
Hesselink DA, van Gelder T, van Schaik RH, Balk AH, van der Heiden IP, van Dam T, van der Werf M, Weimar W, Mathot RA. Hesselink DA, et al. Among authors: van dam t, van gelder t, van der werf m, van schaik rh, van der heiden ip. Clin Pharmacol Ther. 2004 Dec;76(6):545-56. doi: 10.1016/j.clpt.2004.08.022. Clin Pharmacol Ther. 2004. PMID: 15592326
UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients.
van Schaik RH, van Agteren M, de Fijter JW, Hartmann A, Schmidt J, Budde K, Kuypers D, Le Meur Y, van der Werf M, Mamelok R, van Gelder T. van Schaik RH, et al. Among authors: van agteren m, van der werf m, van gelder t. Clin Pharmacol Ther. 2009 Sep;86(3):319-27. doi: 10.1038/clpt.2009.83. Epub 2009 Jun 3. Clin Pharmacol Ther. 2009. PMID: 19494809 Clinical Trial.
Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus.
Hesselink DA, van Schaik RH, van der Heiden IP, van der Werf M, Gregoor PJ, Lindemans J, Weimar W, van Gelder T. Hesselink DA, et al. Among authors: van der werf m, van gelder t, van schaik rh, van der heiden ip. Clin Pharmacol Ther. 2003 Sep;74(3):245-54. doi: 10.1016/S0009-9236(03)00168-1. Clin Pharmacol Ther. 2003. PMID: 12966368
Sequencing: not always the "gold standard".
van der Heiden IP, van der Werf M, Lindemans J, van Schaik RH. van der Heiden IP, et al. Among authors: van der werf m, van schaik rh. Clin Chem. 2004 Jan;50(1):248-9. doi: 10.1373/clinchem.2003.024604. Clin Chem. 2004. PMID: 14709666 No abstract available.
Interpatient variability in IMPDH activity in MMF-treated renal transplant patients is correlated with IMPDH type II 3757T > C polymorphism.
Sombogaard F, van Schaik RH, Mathot RA, Budde K, van der Werf M, Vulto AG, Weimar W, Glander P, Essioux L, van Gelder T. Sombogaard F, et al. Among authors: van der werf m, van gelder t, van schaik rh. Pharmacogenet Genomics. 2009 Aug;19(8):626-34. doi: 10.1097/FPC.0b013e32832f5f1b. Pharmacogenet Genomics. 2009. PMID: 19617864
AcylMPAG plasma concentrations and mycophenolic acid-related side effects in patients undergoing renal transplantation are not related to the UGT2B7-840G>A gene polymorphism.
van Agteren M, Armstrong VW, van Schaik RH, de Fijter H, Hartmann A, Zeier M, Budde K, Kuypers D, Pisarski P, Le Meur Y, van der Werf M, Mamelok RD, Oellerich M, van Gelder T. van Agteren M, et al. Among authors: van der werf m, van gelder t, van schaik rh. Ther Drug Monit. 2008 Aug;30(4):439-44. doi: 10.1097/FTD.0b013e318180c709. Ther Drug Monit. 2008. PMID: 18641546 Clinical Trial.
A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels.
Smit P, van Schaik RH, van der Werf M, van den Beld AW, Koper JW, Lindemans J, Pols HA, Brinkmann AO, de Jong FH, Lamberts SW. Smit P, et al. Among authors: van der werf m, van den beld aw, van schaik rh. J Clin Endocrinol Metab. 2005 Sep;90(9):5313-6. doi: 10.1210/jc.2005-0307. Epub 2005 Jun 28. J Clin Endocrinol Metab. 2005. PMID: 15985487
Characteristic SNPs defining the major multidrug-resistant Mycobacterium tuberculosis clusters identified by EuSeqMyTB to support routine surveillance, EU/EEA, 2017 to 2019.
de Neeling AJ, Tagliani E, Ködmön C, van der Werf MJ, van Soolingen D, Cirillo DM, Anthony RM. de Neeling AJ, et al. Among authors: van der werf mj. Euro Surveill. 2024 Mar;29(12):2300583. doi: 10.2807/1560-7917.ES.2024.29.12.2300583. Euro Surveill. 2024. PMID: 38516788 Free PMC article.
HIV diagnoses among people born in Ukraine reported by EU/EEA countries in 2022: impact on regional HIV trends and implications for healthcare planning.
Reyes-Urueña J, Marrone G, Noori T, Kuchukhidze G, Martsynovska V, Hetman L, Basenko A, Bivol S, van der Werf MJ, Pharris A; EU/EEA HIV network. Reyes-Urueña J, et al. Among authors: van der werf mj. Euro Surveill. 2023 Nov;28(48):2300642. doi: 10.2807/1560-7917.ES.2023.28.48.2300642. Euro Surveill. 2023. PMID: 38037726 Free PMC article.
243 results