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Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.
Hesselink DA, van Gelder T, van Schaik RH, Balk AH, van der Heiden IP, van Dam T, van der Werf M, Weimar W, Mathot RA. Hesselink DA, et al. Among authors: van dam t, van gelder t, van der werf m, van schaik rh, van der heiden ip. Clin Pharmacol Ther. 2004 Dec;76(6):545-56. doi: 10.1016/j.clpt.2004.08.022. Clin Pharmacol Ther. 2004. PMID: 15592326
The CYP3A4*3 allele: is it really rare?
van Schaik RH, de Wildt SN, Brosens R, van Fessem M, van den Anker JN, Lindemans J. van Schaik RH, et al. Among authors: van fessem m, van den anker jn. Clin Chem. 2001 Jun;47(6):1104-6. Clin Chem. 2001. PMID: 11375299 No abstract available.
CYP3A5 variant allele frequencies in Dutch Caucasians.
van Schaik RH, van der Heiden IP, van den Anker JN, Lindemans J. van Schaik RH, et al. Among authors: van den anker jn, van der heiden ip. Clin Chem. 2002 Oct;48(10):1668-71. Clin Chem. 2002. PMID: 12324482
Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus.
Hesselink DA, van Schaik RH, van der Heiden IP, van der Werf M, Gregoor PJ, Lindemans J, Weimar W, van Gelder T. Hesselink DA, et al. Among authors: van der werf m, van gelder t, van schaik rh, van der heiden ip. Clin Pharmacol Ther. 2003 Sep;74(3):245-54. doi: 10.1016/S0009-9236(03)00168-1. Clin Pharmacol Ther. 2003. PMID: 12966368
Sequencing: not always the "gold standard".
van der Heiden IP, van der Werf M, Lindemans J, van Schaik RH. van der Heiden IP, et al. Among authors: van der werf m, van schaik rh. Clin Chem. 2004 Jan;50(1):248-9. doi: 10.1373/clinchem.2003.024604. Clin Chem. 2004. PMID: 14709666 No abstract available.
A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels.
Smit P, van Schaik RH, van der Werf M, van den Beld AW, Koper JW, Lindemans J, Pols HA, Brinkmann AO, de Jong FH, Lamberts SW. Smit P, et al. Among authors: van der werf m, van den beld aw, van schaik rh. J Clin Endocrinol Metab. 2005 Sep;90(9):5313-6. doi: 10.1210/jc.2005-0307. Epub 2005 Jun 28. J Clin Endocrinol Metab. 2005. PMID: 15985487
421 results