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Page 1
Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease.
Peng M, Falk MJ, Haase VH, King R, Polyak E, Selak M, Yudkoff M, Hancock WW, Meade R, Saiki R, Lunceford AL, Clarke CF, Gasser DL. Peng M, et al. Among authors: clarke cf. PLoS Genet. 2008 Apr 25;4(4):e1000061. doi: 10.1371/journal.pgen.1000061. PLoS Genet. 2008. PMID: 18437205 Free PMC article.
Target identification using drug affinity responsive target stability (DARTS).
Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J. Lomenick B, et al. Among authors: clarke cf. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21984-9. doi: 10.1073/pnas.0910040106. Epub 2009 Dec 7. Proc Natl Acad Sci U S A. 2009. PMID: 19995983 Free PMC article.
Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport.
Pfeiffer M, Kayzer EB, Yang X, Abramson E, Kenaston MA, Lago CU, Lo HH, Sedensky MM, Lunceford A, Clarke CF, Wu SJ, McLeod C, Finkel T, Morgan PG, Mills EM. Pfeiffer M, et al. Among authors: clarke cf. J Biol Chem. 2011 Oct 28;286(43):37712-20. doi: 10.1074/jbc.M111.271452. Epub 2011 Aug 23. J Biol Chem. 2011. PMID: 21862587 Free PMC article.
A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.
Allan CM, Hill S, Morvaridi S, Saiki R, Johnson JS, Liau WS, Hirano K, Kawashima T, Ji Z, Loo JA, Shepherd JN, Clarke CF. Allan CM, et al. Among authors: clarke cf. Biochim Biophys Acta. 2013 Apr;1831(4):776-791. doi: 10.1016/j.bbalip.2012.12.007. Epub 2012 Dec 25. Biochim Biophys Acta. 2013. PMID: 23270816 Free PMC article.
Osmotic stress: Is CoQ a membrane stabilizer?
Clarke CF, Rowat AC, Gober JW. Clarke CF, et al. Nat Chem Biol. 2014 Apr;10(4):242-3. doi: 10.1038/nchembio.1478. Nat Chem Biol. 2014. PMID: 24643237 No abstract available.
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.
Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. Chin RM, et al. Among authors: clarke cf. Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14. Nature. 2014. PMID: 24828042 Free PMC article.
141 results