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A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.
Love-Gregory LD, Wasson J, Ma J, Jin CH, Glaser B, Suarez BK, Permutt MA. Love-Gregory LD, et al. Among authors: permutt ma, ma j. Diabetes. 2004 Apr;53(4):1134-40. doi: 10.2337/diabetes.53.4.1134. Diabetes. 2004. PMID: 15047632
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.
Barroso I, Luan J, Wheeler E, Whittaker P, Wasson J, Zeggini E, Weedon MN, Hunt S, Venkatesh R, Frayling TM, Delgado M, Neuman RJ, Zhao J, Sherva R, Glaser B, Walker M, Hitman G, McCarthy MI, Hattersley AT, Permutt MA, Wareham NJ, Deloukas P. Barroso I, et al. Among authors: permutt ma. Diabetes. 2008 Nov;57(11):3161-5. doi: 10.2337/db08-0719. Epub 2008 Aug 26. Diabetes. 2008. PMID: 18728231 Free PMC article.
Searching for type 2 diabetes genes on chromosome 20.
Permutt MA, Wasson J, Love-Gregory L, Ma J, Skolnick G, Suarez B, Lin J, Glaser B. Permutt MA, et al. Among authors: ma j. Diabetes. 2002 Dec;51 Suppl 3:S308-15. doi: 10.2337/diabetes.51.2007.s308. Diabetes. 2002. PMID: 12475768
HNF4A genetic variants: role in diabetes.
Love-Gregory L, Permutt MA. Love-Gregory L, et al. Among authors: permutt ma. Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):397-402. doi: 10.1097/MCO.0b013e3281e3888d. Curr Opin Clin Nutr Metab Care. 2007. PMID: 17563455 Review.
Common variants in WFS1 confer risk of type 2 diabetes.
Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, Lango H, Frayling TM, Neumann RJ, Sherva R, Blech I, Pharoah PD, Palmer CN, Kimber C, Tavendale R, Morris AD, McCarthy MI, Walker M, Hitman G, Glaser B, Permutt MA, Hattersley AT, Wareham NJ, Barroso I. Sandhu MS, et al. Among authors: permutt ma. Nat Genet. 2007 Aug;39(8):951-3. doi: 10.1038/ng2067. Epub 2007 Jul 1. Nat Genet. 2007. PMID: 17603484 Free PMC article.
Gene expression profiling in islet biology and diabetes research.
Bernal-Mizrachi E, Cras-Méneur C, Ohsugi M, Permutt MA. Bernal-Mizrachi E, et al. Among authors: permutt ma. Diabetes Metab Res Rev. 2003 Jan-Feb;19(1):32-42. doi: 10.1002/dmrr.331. Diabetes Metab Res Rev. 2003. PMID: 12592642 Review.
207 results