Holm J - Search Results

1

Allergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE binding but retains protein folding pattern for induction of protective blocking-antibody responses.

Holm J, Gajhede M, Ferreras M, Henriksen A, Ipsen H, Larsen JN, Lund L, Jacobi H, Millner A, Würtzen PA, Spangfort MD. Holm J, et al. J Immunol. 2004 Oct 15;173(8):5258-67. doi: 10.4049/jimmunol.173.8.5258. J Immunol. 2004. PMID: 15470071

2

Chemical modification of birch allergen extract leads to a reduction in allergenicity as well as immunogenicity.

Würtzen PA, Lund L, Lund G, Holm J, Millner A, Henmar H. Würtzen PA, et al. Among authors: holm j. Int Arch Allergy Immunol. 2007;144(4):287-95. doi: 10.1159/000106317. Epub 2007 Jul 20. Int Arch Allergy Immunol. 2007. PMID: 17641548

3

Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1.

Holm J, Ferreras M, Ipsen H, Würtzen PA, Gajhede M, Larsen JN, Lund K, Spangfort MD. Holm J, et al. J Biol Chem. 2011 May 20;286(20):17569-78. doi: 10.1074/jbc.M110.194878. Epub 2011 Mar 24. J Biol Chem. 2011. PMID: 21454600 Free PMC article.

4

The complexity of allergic patients' IgE repertoire correlates with serum concentration of allergen-specific IgE.

Willumsen N, Holm J, Christensen LH, Würtzen PA, Lund K. Willumsen N, et al. Among authors: holm j. Clin Exp Allergy. 2012 Aug;42(8):1227-36. doi: 10.1111/j.1365-2222.2012.04009.x. Clin Exp Allergy. 2012. PMID: 22805470

5

Effect on cell surface markers following allergen-induced desensitization of human whole-blood basophils.

Lund G, Jacobi H, Skov PS, Holm J, Lund K. Lund G, et al. Among authors: holm j. Int Arch Allergy Immunol. 2010;153(4):323-34. doi: 10.1159/000316343. Epub 2010 Jun 17. Int Arch Allergy Immunol. 2010. PMID: 20558998

6

Facilitated antigen presentation and its inhibition by blocking IgG antibodies depends on IgE repertoire complexity.

Holm J, Willumsen N, Würtzen PA, Christensen LH, Lund K. Holm J, et al. J Allergy Clin Immunol. 2011 Apr;127(4):1029-37. doi: 10.1016/j.jaci.2011.01.062. Epub 2011 Mar 5. J Allergy Clin Immunol. 2011. PMID: 21377718

7

Antibody repertoire complexity and effector cell biology determined by assays for IgE-mediated basophil and T-cell activation.

Lund G, Willumsen N, Holm J, Christensen LH, Würtzen PA, Lund K. Lund G, et al. Among authors: holm j. J Immunol Methods. 2012 Sep 28;383(1-2):4-20. doi: 10.1016/j.jim.2012.05.021. Epub 2012 Jun 7. J Immunol Methods. 2012. PMID: 22683539 Review.

8

Molecular basis of allergic cross-reactivity between group 1 major allergens from birch and apple.

Holm J, Baerentzen G, Gajhede M, Ipsen H, Larsen JN, Løwenstein H, Wissenbach M, Spangfort MD. Holm J, et al. J Chromatogr B Biomed Sci Appl. 2001 May 25;756(1-2):307-13. doi: 10.1016/s0378-4347(01)00089-5. J Chromatogr B Biomed Sci Appl. 2001. PMID: 11419722

9

Elimination of a misfolded folding intermediate by a single point mutation.

Mogensen JE, Ipsen H, Holm J, Otzen DE. Mogensen JE, et al. Among authors: holm j. Biochemistry. 2004 Mar 30;43(12):3357-67. doi: 10.1021/bi0358622. Biochemistry. 2004. PMID: 15035607

10

Immunoproteomic analysis of house dust mite antigens reveals distinct classes of dominant T cell antigens according to function and serological reactivity.

Oseroff C, Christensen LH, Westernberg L, Pham J, Lane J, Paul S, Greenbaum J, Stranzl T, Lund G, Hoof I, Holm J, Würtzen PA, Meno KH, Frazier A, Schulten V, Andersen PS, Peters B, Sette A. Oseroff C, et al. Among authors: holm j. Clin Exp Allergy. 2017 Apr;47(4):577-592. doi: 10.1111/cea.12829. Epub 2016 Nov 7. Clin Exp Allergy. 2017. PMID: 27684489 Free PMC article.

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