Holmes RK - Search Results

1

Functional studies of the Mycobacterium tuberculosis iron-dependent regulator.

Chou CJ, Wisedchaisri G, Monfeli RR, Oram DM, Holmes RK, Hol WG, Beeson C. Chou CJ, et al. Among authors: holmes rk. J Biol Chem. 2004 Dec 17;279(51):53554-61. doi: 10.1074/jbc.M407385200. Epub 2004 Sep 29. J Biol Chem. 2004. PMID: 15456786 Free article.

2

Crystal structure of an IdeR-DNA complex reveals a conformational change in activated IdeR for base-specific interactions.

Wisedchaisri G, Holmes RK, Hol WG. Wisedchaisri G, et al. Among authors: holmes rk. J Mol Biol. 2004 Sep 24;342(4):1155-69. doi: 10.1016/j.jmb.2004.07.083. J Mol Biol. 2004. PMID: 15351642

3

Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis.

Wisedchaisri G, Chou CJ, Wu M, Roach C, Rice AE, Holmes RK, Beeson C, Hol WG. Wisedchaisri G, et al. Among authors: holmes rk. Biochemistry. 2007 Jan 16;46(2):436-47. doi: 10.1021/bi0609826. Biochemistry. 2007. PMID: 17209554

4

Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.

Pohl E, Holmes RK, Hol WG. Pohl E, et al. Among authors: holmes rk. J Biol Chem. 1998 Aug 28;273(35):22420-7. doi: 10.1074/jbc.273.35.22420. J Biol Chem. 1998. PMID: 9712865 Free article.

5

Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.

Feese MD, Ingason BP, Goranson-Siekierke J, Holmes RK, Hol WG. Feese MD, et al. Among authors: holmes rk. J Biol Chem. 2001 Feb 23;276(8):5959-66. doi: 10.1074/jbc.M007531200. Epub 2000 Oct 26. J Biol Chem. 2001. PMID: 11053439 Free article.

6

Analysis of truncated variants of the iron dependent transcriptional regulators from Corynebacterium diphtheriae and Mycobacterium tuberculosis.

Oram DM, Must LM, Spinler JK, Twiddy EM, Holmes RK. Oram DM, et al. Among authors: holmes rk. FEMS Microbiol Lett. 2005 Feb 1;243(1):1-8. doi: 10.1016/j.femsle.2004.11.031. FEMS Microbiol Lett. 2005. PMID: 15667993

7

Structural basis for the activation of cholera toxin by human ARF6-GTP.

O'Neal CJ, Jobling MG, Holmes RK, Hol WG. O'Neal CJ, et al. Among authors: holmes rk. Science. 2005 Aug 12;309(5737):1093-6. doi: 10.1126/science.1113398. Science. 2005. PMID: 16099990

8

Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors.

Qiu X, Verlinde CL, Zhang S, Schmitt MP, Holmes RK, Hol WG. Qiu X, et al. Among authors: holmes rk. Structure. 1995 Jan 15;3(1):87-100. doi: 10.1016/s0969-2126(01)00137-x. Structure. 1995. PMID: 7743135 Free article.

9

High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.

Qiu X, Pohl E, Holmes RK, Hol WG. Qiu X, et al. Among authors: holmes rk. Biochemistry. 1996 Sep 24;35(38):12292-302. doi: 10.1021/bi960861d. Biochemistry. 1996. PMID: 8823163

10

Comparison of high-resolution structures of the diphtheria toxin repressor in complex with cobalt and zinc at the cation-anion binding site.

Pohl E, Qui X, Must LM, Holmes RK, Hol WG. Pohl E, et al. Among authors: holmes rk. Protein Sci. 1997 May;6(5):1114-8. doi: 10.1002/pro.5560060519. Protein Sci. 1997. PMID: 9144784 Free PMC article.

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