Lewi P - Search Results

1

A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides.

Van Herrewege Y, Vanham G, Michiels J, Fransen K, Kestens L, Andries K, Janssen P, Lewi P. Van Herrewege Y, et al. Among authors: lewi p. Antimicrob Agents Chemother. 2004 Oct;48(10):3684-9. doi: 10.1128/AAC.48.10.3684-3689.2004. Antimicrob Agents Chemother. 2004. PMID: 15388420 Free PMC article.

2

In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides.

Van Herrewege Y, Michiels J, Van Roey J, Fransen K, Kestens L, Balzarini J, Lewi P, Vanham G, Janssen P. Van Herrewege Y, et al. Among authors: lewi p. Antimicrob Agents Chemother. 2004 Jan;48(1):337-9. doi: 10.1128/AAC.48.1.337-339.2004. Antimicrob Agents Chemother. 2004. PMID: 14693562 Free PMC article.

3

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides.

Van Herrewege Y, Michiels J, Waeytens A, De Boeck G, Salden E, Heyndrickx L, van den Mooter G, de Béthune MP, Andries K, Lewi P, Praet M, Vanham G. Van Herrewege Y, et al. Among authors: lewi p. Antiviral Res. 2007 May;74(2):111-24. doi: 10.1016/j.antiviral.2006.10.010. Epub 2006 Nov 7. Antiviral Res. 2007. PMID: 17097156

4

Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection.

Terrazas-Aranda K, Van Herrewege Y, Hazuda D, Lewi P, Costi R, Di Santo R, Cara A, Vanham G. Terrazas-Aranda K, et al. Among authors: lewi p. Antimicrob Agents Chemother. 2008 Jul;52(7):2544-54. doi: 10.1128/AAC.01627-07. Epub 2008 May 12. Antimicrob Agents Chemother. 2008. PMID: 18474579 Free PMC article.

5

Pre-incubation of cell-free HIV-1 group M isolates with non-nucleoside reverse transcriptase inhibitors blocks subsequent viral replication in co-cultures of dendritic cells and T cells.

Njai HF, Lewi PJ, Janssen CG, Garcia S, Fransen K, Kestens L, Vanham G, Janssen PA. Njai HF, et al. Antivir Ther. 2005;10(2):255-62. Antivir Ther. 2005. PMID: 15865220

6

In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection.

Terrazas-Aranda K, Van Herrewege Y, Lewi PJ, Van Roey J, Vanham G. Terrazas-Aranda K, et al. Antivir Chem Chemother. 2007;18(3):141-51. doi: 10.1177/095632020701800304. Antivir Chem Chemother. 2007. PMID: 17626598 Free article.

7

Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission.

Ariën KK, Venkatraj M, Michiels J, Joossens J, Vereecken K, Van der Veken P, Abdellati S, Cuylaerts V, Crucitti T, Heyndrickx L, Heeres J, Augustyns K, Lewi PJ, Vanham G. Ariën KK, et al. Among authors: lewi pj. J Antimicrob Chemother. 2013 Sep;68(9):2038-47. doi: 10.1093/jac/dkt166. Epub 2013 May 3. J Antimicrob Chemother. 2013. PMID: 23645585

8

Antiviral compounds show enhanced activity in HIV-1 single cycle pseudovirus assays as compared to classical PBMC assays.

Heyndrickx L, Vermoesen T, Vereecken K, Kurth J, Coppens S, Aerts L, Ohagen A, Van Herrewege Y, Lewi P, Vanham G. Heyndrickx L, et al. Among authors: lewi p. J Virol Methods. 2008 Mar;148(1-2):166-73. doi: 10.1016/j.jviromet.2007.11.009. Epub 2008 Jan 14. J Virol Methods. 2008. PMID: 18192031

9

2,6-Di(arylamino)-3-fluoropyridine Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.

Sergeyev S, Yadav AK, Franck P, Michiels J, Lewi P, Heeres J, Vanham G, Ariën KK, Vande Velde CM, De Winter H, Maes BU. Sergeyev S, et al. Among authors: lewi p. J Med Chem. 2016 Mar 10;59(5):1854-68. doi: 10.1021/acs.jmedchem.5b01336. Epub 2016 Feb 8. J Med Chem. 2016. PMID: 26785139

10

Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).

Venkatraj M, Ariën KK, Heeres J, Dirié B, Joossens J, Van Goethem S, Van der Veken P, Michiels J, Vande Velde CM, Vanham G, Lewi PJ, Augustyns K. Venkatraj M, et al. Among authors: lewi pj. Bioorg Med Chem. 2011 Oct 15;19(20):5924-34. doi: 10.1016/j.bmc.2011.08.060. Epub 2011 Sep 1. Bioorg Med Chem. 2011. PMID: 21930388

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