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IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8 CTL in tuberculosis patients.
de la Barrera S, Aleman M, Musella R, Schierloh P, Pasquinelli V, Garcia V, Abbate E, Sasiain Mdel C. de la Barrera S, et al. Among authors: sasiain mdel c. Clin Exp Immunol. 2004 Oct;138(1):128-38. doi: 10.1111/j.1365-2249.2004.02577.x. Clin Exp Immunol. 2004. PMID: 15373915 Free PMC article.
Monocytes and neutrophils from tuberculosis patients are insensitive to anti-inflammatory effects triggered by the prototypic formyl peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP).
Beigier-Bompadre M, Alemán M, Barrionuevo P, Franco MC, Rubel CJ, Sasiain Mdel C, Palermo MS, Abbate E, Isturiz MA. Beigier-Bompadre M, et al. Among authors: sasiain mdel c. Clin Exp Immunol. 2003 Aug;133(2):267-74. doi: 10.1046/j.1365-2249.2003.02212.x. Clin Exp Immunol. 2003. PMID: 12869034 Free PMC article.
Toll-like receptors in human infectious diseases.
de la Barrera S, Alemán M, Sasiain Mdel C. de la Barrera S, et al. Among authors: sasiain mdel c. Curr Pharm Des. 2006;12(32):4173-84. doi: 10.2174/138161206778743493. Curr Pharm Des. 2006. PMID: 17100620 Review.
Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis.
Lastrucci C, Bénard A, Balboa L, Pingris K, Souriant S, Poincloux R, Al Saati T, Rasolofo V, González-Montaner P, Inwentarz S, Moraña EJ, Kondova I, Verreck FA, Sasiain Mdel C, Neyrolles O, Maridonneau-Parini I, Lugo-Villarino G, Cougoule C. Lastrucci C, et al. Among authors: sasiain mdel c. Cell Res. 2015 Dec;25(12):1333-51. doi: 10.1038/cr.2015.123. Epub 2015 Oct 20. Cell Res. 2015. PMID: 26482950 Free PMC article.
Diverging biological roles among human monocyte subsets in the context of tuberculosis infection.
Balboa L, Barrios-Payan J, González-Domínguez E, Lastrucci C, Lugo-Villarino G, Mata-Espinoza D, Schierloh P, Kviatcovsky D, Neyrolles O, Maridonneau-Parini I, Sánchez-Torres C, Sasiain Mdel C, Hernández-Pando R. Balboa L, et al. Among authors: sasiain mdel c. Clin Sci (Lond). 2015 Aug;129(4):319-30. doi: 10.1042/CS20150021. Clin Sci (Lond). 2015. PMID: 25858460
Two genetically-related multidrug-resistant Mycobacterium tuberculosis strains induce divergent outcomes of infection in two human macrophage models.
Yokobori N, López B, Geffner L, Sabio y García C, Schierloh P, Barrera L, de la Barrera S, Sakai S, Kawamura I, Mitsuyama M, Ritacco V, Sasiain Mdel C. Yokobori N, et al. Among authors: sasiain mdel c. Infect Genet Evol. 2013 Jun;16:151-6. doi: 10.1016/j.meegid.2013.01.007. Epub 2013 Jan 24. Infect Genet Evol. 2013. PMID: 23352891
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