Hancock JF - Search Results

1

Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane.

Rotblat B, Prior IA, Muncke C, Parton RG, Kloog Y, Henis YI, Hancock JF. Rotblat B, et al. Among authors: hancock jf. Mol Cell Biol. 2004 Aug;24(15):6799-810. doi: 10.1128/MCB.24.15.6799-6810.2004. Mol Cell Biol. 2004. PMID: 15254246 Free PMC article.

2

N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization.

Cadwallader KA, Paterson H, Macdonald SG, Hancock JF. Cadwallader KA, et al. Among authors: hancock jf. Mol Cell Biol. 1994 Jul;14(7):4722-30. doi: 10.1128/mcb.14.7.4722-4730.1994. Mol Cell Biol. 1994. PMID: 8007974 Free PMC article.

3

The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization.

Beranger F, Paterson H, Powers S, de Gunzburg J, Hancock JF. Beranger F, et al. Among authors: hancock jf. Mol Cell Biol. 1994 Jan;14(1):744-58. doi: 10.1128/mcb.14.1.744-758.1994. Mol Cell Biol. 1994. PMID: 8264642 Free PMC article.

4

Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function.

Huang DC, Marshall CJ, Hancock JF. Huang DC, et al. Among authors: hancock jf. Mol Cell Biol. 1993 Apr;13(4):2420-31. doi: 10.1128/mcb.13.4.2420-2431.1993. Mol Cell Biol. 1993. PMID: 8455619 Free PMC article.

5

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger.

Roy S, Lane A, Yan J, McPherson R, Hancock JF. Roy S, et al. Among authors: hancock jf. J Biol Chem. 1997 Aug 8;272(32):20139-45. doi: 10.1074/jbc.272.32.20139. J Biol Chem. 1997. PMID: 9242688 Free article.

6

14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo.

Roy S, McPherson RA, Apolloni A, Yan J, Lane A, Clyde-Smith J, Hancock JF. Roy S, et al. Among authors: hancock jf. Mol Cell Biol. 1998 Jul;18(7):3947-55. doi: 10.1128/MCB.18.7.3947. Mol Cell Biol. 1998. PMID: 9632779 Free PMC article.

7

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase.

Yan J, Roy S, Apolloni A, Lane A, Hancock JF. Yan J, et al. Among authors: hancock jf. J Biol Chem. 1998 Sep 11;273(37):24052-6. doi: 10.1074/jbc.273.37.24052. J Biol Chem. 1998. PMID: 9727023 Free article.

8

Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains.

Roy S, Luetterforst R, Harding A, Apolloni A, Etheridge M, Stang E, Rolls B, Hancock JF, Parton RG. Roy S, et al. Among authors: hancock jf. Nat Cell Biol. 1999 Jun;1(2):98-105. doi: 10.1038/10067. Nat Cell Biol. 1999. PMID: 10559881

9

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway.

Apolloni A, Prior IA, Lindsay M, Parton RG, Hancock JF. Apolloni A, et al. Among authors: hancock jf. Mol Cell Biol. 2000 Apr;20(7):2475-87. doi: 10.1128/MCB.20.7.2475-2487.2000. Mol Cell Biol. 2000. PMID: 10713171 Free PMC article.

10

Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor.

Clyde-Smith J, Silins G, Gartside M, Grimmond S, Etheridge M, Apolloni A, Hayward N, Hancock JF. Clyde-Smith J, et al. Among authors: hancock jf. J Biol Chem. 2000 Oct 13;275(41):32260-7. doi: 10.1074/jbc.M006087200. J Biol Chem. 2000. PMID: 10918068 Free article.

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