Kempf DJ - Search Results

1

Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.

Huang PP, Randolph JT, Klein LL, Vasavanonda S, Dekhtyar T, Stoll VS, Kempf DJ. Huang PP, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2004 Aug 2;14(15):4075-8. doi: 10.1016/j.bmcl.2004.05.036. Bioorg Med Chem Lett. 2004. PMID: 15225729

2

Synthesis and structure-activity relationships of a novel series of HIV-1 protease inhibitors encompassing ABT-378 (Lopinavir).

Sham HL, Betebenner DA, Chen X, Saldivar A, Vasavanonda S, Kempf DJ, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1185-7. doi: 10.1016/s0960-894x(02)00134-8. Bioorg Med Chem Lett. 2002. PMID: 11934584

3

Novel lopinavir analogues incorporating non-Aromatic P-1 side chains--synthesis and structure--activity relationships.

Sham HL, Zhao C, Li L, Betebenner DA, Saldivar A, Vasavanonda S, Kempf DJ, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3101-3. doi: 10.1016/s0960-894x(02)00643-1. Bioorg Med Chem Lett. 2002. PMID: 12372511

4

Synthesis and SAR studies of potent HIV protease inhibitors containing novel dimethylphenoxyl acetates as P2 ligands.

Chen X, Kempf DJ, Li L, Sham HL, Vasavanonda S, Wideburg NE, Saldivar A, Marsh KC, McDonald E, Norbeck DW. Chen X, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3657-60. doi: 10.1016/j.bmcl.2003.08.043. Bioorg Med Chem Lett. 2003. PMID: 14552751

5

Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.

Wang GT, Wang S, Gentles R, Sowin T, Maring CJ, Kempf DJ, Kati WM, Stoll V, Stewart KD, Laver G. Wang GT, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2005 Jan 3;15(1):125-8. doi: 10.1016/j.bmcl.2004.10.022. Bioorg Med Chem Lett. 2005. PMID: 15582424

6

Oximinoarylsulfonamides as potent HIV protease inhibitors.

Yeung CM, Klein LL, Flentge CA, Randolph JT, Zhao C, Sun M, Dekhtyar T, Stoll VS, Kempf DJ. Yeung CM, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2005 May 2;15(9):2275-8. doi: 10.1016/j.bmcl.2005.03.008. Bioorg Med Chem Lett. 2005. PMID: 15837308

7

Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors.

Maring CJ, Stoll VS, Zhao C, Sun M, Krueger AC, Stewart KD, Madigan DL, Kati WM, Xu Y, Carrick RJ, Montgomery DA, Kempf-Grote A, Marsh KC, Molla A, Steffy KR, Sham HL, Laver WG, Gu YG, Kempf DJ, Kohlbrenner WE. Maring CJ, et al. Among authors: kempf dj, kempf grote a. J Med Chem. 2005 Jun 16;48(12):3980-90. doi: 10.1021/jm049276y. J Med Chem. 2005. PMID: 15943472

8

Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains.

Zhao C, Sham HL, Sun M, Stoll VS, Stewart KD, Lin S, Mo H, Vasavanonda S, Saldivar A, Park C, McDonald EJ, Marsh KC, Klein LL, Kempf DJ, Norbeck DW. Zhao C, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5499-503. doi: 10.1016/j.bmcl.2005.08.093. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203141

9

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors.

Randolph JT, Huang PP, Flosi WJ, DeGoey D, Klein LL, Yeung CM, Flentge C, Sun M, Zhao C, Dekhtyar T, Mo H, Colletti L, Kati W, Marsh KC, Molla A, Kempf DJ. Randolph JT, et al. Among authors: kempf dj. Bioorg Med Chem. 2006 Jun 15;14(12):4035-46. doi: 10.1016/j.bmc.2006.02.013. Epub 2006 Feb 28. Bioorg Med Chem. 2006. PMID: 16504523

10

Synthesis, antiviral activity, and conformational studies of a P3 aza-peptide analog of a potent macrocyclic tripeptide HCV protease inhibitor.

Randolph JT, Zhang X, Huang PP, Klein LL, Kurtz KA, Konstantinidis AK, He W, Kati WM, Kempf DJ. Randolph JT, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2745-50. doi: 10.1016/j.bmcl.2008.02.053. Epub 2008 Feb 26. Bioorg Med Chem Lett. 2008. PMID: 18375121

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

140 results

Search Page

Filters