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Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2.
Oshima T, Abe M, Asano J, Hara T, Kitazoe K, Sekimoto E, Tanaka Y, Shibata H, Hashimoto T, Ozaki S, Kido S, Inoue D, Matsumoto T. Oshima T, et al. Among authors: hashimoto t. Blood. 2005 Nov 1;106(9):3160-5. doi: 10.1182/blood-2004-12-4940. Epub 2005 Jul 19. Blood. 2005. PMID: 16030194 Free article.
Malignant B-lymphoid cells with bone lesions express receptor activator of nuclear factor-kappaB ligand and vascular endothelial growth factor to enhance osteoclastogenesis.
Shibata H, Abe M, Hiura K, Wilde J, Moriyama K, Sano T, Kitazoe K, Hashimoto T, Ozaki S, Wakatsuki S, Kido S, Inoue D, Matsumoto T. Shibata H, et al. Among authors: hashimoto t. Clin Cancer Res. 2005 Sep 1;11(17):6109-15. doi: 10.1158/1078-0432.CCR-05-0181. Clin Cancer Res. 2005. PMID: 16144909
GM-CSF and IL-4 induce dendritic cell differentiation and disrupt osteoclastogenesis through M-CSF receptor shedding by up-regulation of TNF-alpha converting enzyme (TACE).
Hiasa M, Abe M, Nakano A, Oda A, Amou H, Kido S, Takeuchi K, Kagawa K, Yata K, Hashimoto T, Ozaki S, Asaoka K, Tanaka E, Moriyama K, Matsumoto T. Hiasa M, et al. Among authors: hashimoto t. Blood. 2009 Nov 12;114(20):4517-26. doi: 10.1182/blood-2009-04-215020. Epub 2009 Sep 17. Blood. 2009. PMID: 19762488 Free article.
[Biochemical markers in bone metastasis].
Hashimoto T, Abe M, Matsumoto T. Hashimoto T, et al. Gan To Kagaku Ryoho. 2004 Jul;31(7):1027-33. Gan To Kagaku Ryoho. 2004. PMID: 15272580 Review. Japanese.
6,982 results