Shih DQ - Search Results

1

Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3.

Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT. Kulkarni RN, et al. Among authors: shih dq. Diabetes. 2004 Jun;53(6):1517-25. doi: 10.2337/diabetes.53.6.1517. Diabetes. 2004. PMID: 15161756

2

Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.

Shih DQ, Screenan S, Munoz KN, Philipson L, Pontoglio M, Yaniv M, Polonsky KS, Stoffel M. Shih DQ, et al. Diabetes. 2001 Nov;50(11):2472-80. doi: 10.2337/diabetes.50.11.2472. Diabetes. 2001. PMID: 11679424

3

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.

Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: shih dq. Nat Genet. 2002 May;31(1):111-5. doi: 10.1038/ng872. Epub 2002 Apr 1. Nat Genet. 2002. PMID: 11923875

4

Molecular etiologies of MODY and other early-onset forms of diabetes.

Shih DQ, Stoffel M. Shih DQ, et al. Curr Diab Rep. 2002 Apr;2(2):125-34. doi: 10.1007/s11892-002-0071-9. Curr Diab Rep. 2002. PMID: 12643132 Review.

5

Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.

Richter S, Shih DQ, Pearson ER, Wolfrum C, Fajans SS, Hattersley AT, Stoffel M. Richter S, et al. Among authors: shih dq. Diabetes. 2003 Dec;52(12):2989-95. doi: 10.2337/diabetes.52.12.2989. Diabetes. 2003. PMID: 14633861

6

Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).

Boileau P, Wolfrum C, Shih DQ, Yang TA, Wolkoff AW, Stoffel M. Boileau P, et al. Among authors: shih dq. Diabetes. 2002 Dec;51 Suppl 3:S343-8. doi: 10.2337/diabetes.51.2007.s343. Diabetes. 2002. PMID: 12475773

7

Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.

Shih DQ, Dansky HM, Fleisher M, Assmann G, Fajans SS, Stoffel M. Shih DQ, et al. Diabetes. 2000 May;49(5):832-7. doi: 10.2337/diabetes.49.5.832. Diabetes. 2000. PMID: 10905494

8

Functional characterization of the MODY1 gene mutations HNF4(R127W), HNF4(V255M), and HNF4(E276Q).

Navas MA, Munoz-Elias EJ, Kim J, Shih D, Stoffel M. Navas MA, et al. Diabetes. 1999 Jul;48(7):1459-65. doi: 10.2337/diabetes.48.7.1459. Diabetes. 1999. PMID: 10389854

9

Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M. Shih DQ, et al. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23. doi: 10.1073/pnas.062605899. Proc Natl Acad Sci U S A. 2002. PMID: 11904435 Free PMC article.

10

Dissecting the transcriptional network of pancreatic islets during development and differentiation.

Shih DQ, Stoffel M. Shih DQ, et al. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14189-91. doi: 10.1073/pnas.251558998. Proc Natl Acad Sci U S A. 2001. PMID: 11734636 Free PMC article. No abstract available.

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