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A multicenter, randomized, placebo-controlled, double-blind phase 3 trial with open-arm comparison indicates safety and efficacy of nephroprotective therapy with ramipril in children with Alport's syndrome.
Gross O, Tönshoff B, Weber LT, Pape L, Latta K, Fehrenbach H, Lange-Sperandio B, Zappel H, Hoyer P, Staude H, König S, John U, Gellermann J, Hoppe B, Galiano M, Hoecker B, Ehren R, Lerch C, Kashtan CE, Harden M, Boeckhaus J, Friede T; German Pediatric Nephrology (GPN) Study Group and EARLY PRO-TECT Alport Investigators. Gross O, et al. Among authors: lerch c. Kidney Int. 2020 Jun;97(6):1275-1286. doi: 10.1016/j.kint.2019.12.015. Epub 2020 Jan 17. Kidney Int. 2020. PMID: 32299679 Free article. Clinical Trial.
The role of protocol biopsies after pediatric kidney transplantation.
Kanzelmeyer NK, Lerch C, Ahlenstiel-Grunow T, Bräsen JH, Haffner D, Pape L. Kanzelmeyer NK, et al. Among authors: lerch c. Medicine (Baltimore). 2020 Jun 5;99(23):e20522. doi: 10.1097/MD.0000000000020522. Medicine (Baltimore). 2020. PMID: 32502003 Free PMC article.
Effects of nutritional vitamin D supplementation on markers of bone and mineral metabolism in children with chronic kidney disease.
Lerch C, Shroff R, Wan M, Rees L, Aitkenhead H, Kaplan Bulut I, Thurn D, Karabay Bayazit A, Niemirska A, Canpolat N, Duzova A, Azukaitis K, Yilmaz E, Yalcinkaya F, Harambat J, Kiyak A, Alpay H, Habbig S, Zaloszyc A, Soylemezoglu O, Candan C, Rosales A, Melk A, Querfeld U, Leifheit-Nestler M, Sander A, Schaefer F, Haffner D; 4C study consortium; ESPN CKD-MBD working group. Lerch C, et al. Nephrol Dial Transplant. 2018 Dec 1;33(12):2208-2217. doi: 10.1093/ndt/gfy012. Nephrol Dial Transplant. 2018. PMID: 29481636 Clinical Trial.
47 results