Brandts C - Search Results

1

High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.

Müller-Tidow C, Schwäble J, Steffen B, Tidow N, Brandt B, Becker K, Schulze-Bahr E, Halfter H, Vogt U, Metzger R, Schneider PM, Büchner T, Brandts C, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: brandts c. Clin Cancer Res. 2004 Feb 15;10(4):1241-9. doi: 10.1158/1078-0432.ccr-0954-03. Clin Cancer Res. 2004. PMID: 14977821

2

[Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms].

Müller-Tidow C, Steur C, Mizuki M, Schwäble J, Brandts C, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: brandts c. Dtsch Med Wochenschr. 2002 Oct 18;127(42):2195-200. doi: 10.1055/s-2002-34942. Dtsch Med Wochenschr. 2002. PMID: 12397548 German.

3

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

Schwäble J, Choudhary C, Thiede C, Tickenbrock L, Sargin B, Steur C, Rehage M, Rudat A, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Schwäble J, et al. Among authors: brandts c. Blood. 2005 Mar 1;105(5):2107-14. doi: 10.1182/blood-2004-03-0940. Epub 2004 Nov 9. Blood. 2005. PMID: 15536149 Free article.

4

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

Tickenbrock L, Schwäble J, Wiedehage M, Steffen B, Sargin B, Choudhary C, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Tickenbrock L, et al. Among authors: brandts c. Blood. 2005 May 1;105(9):3699-706. doi: 10.1182/blood-2004-07-2924. Epub 2005 Jan 13. Blood. 2005. PMID: 15650056 Free article.

5

Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer.

Müller-Tidow C, Diederichs S, Bulk E, Pohle T, Steffen B, Schwäble J, Plewka S, Thomas M, Metzger R, Schneider PM, Brandts CH, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: brandts ch. Cancer Res. 2005 Mar 1;65(5):1778-82. doi: 10.1158/0008-5472.CAN-04-3388. Cancer Res. 2005. PMID: 15753374

6

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

Choudhary C, Schwäble J, Brandts C, Tickenbrock L, Sargin B, Kindler T, Fischer T, Berdel WE, Müller-Tidow C, Serve H. Choudhary C, et al. Among authors: brandts c. Blood. 2005 Jul 1;106(1):265-73. doi: 10.1182/blood-2004-07-2942. Epub 2005 Mar 15. Blood. 2005. PMID: 15769897 Free article.

7

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain.

Heidel F, Solem FK, Breitenbuecher F, Lipka DB, Kasper S, Thiede MH, Brandts C, Serve H, Roesel J, Giles F, Feldman E, Ehninger G, Schiller GJ, Nimer S, Stone RM, Wang Y, Kindler T, Cohen PS, Huber C, Fischer T. Heidel F, et al. Among authors: brandts c. Blood. 2006 Jan 1;107(1):293-300. doi: 10.1182/blood-2005-06-2469. Epub 2005 Sep 8. Blood. 2006. PMID: 16150941 Free article.

8

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwäble J, Buerger H, Müller-Tidow C, Choudhary C, McMahon M, Berdel WE, Serve H. Brandts CH, et al. Cancer Res. 2005 Nov 1;65(21):9643-50. doi: 10.1158/0008-5472.CAN-05-0422. Cancer Res. 2005. PMID: 16266983

9

Acetylsalicylic acid enhances antiproliferative effects of the EGFR inhibitor gefitinib in the absence of activating mutations in gastric cancer.

Becker JC, Müller-Tidow C, Stolte M, Fujimori T, Tidow N, Ilea AM, Brandts C, Tickenbrock L, Serve H, Berdel WE, Domschke W, Pohle T. Becker JC, et al. Among authors: brandts c. Int J Oncol. 2006 Sep;29(3):615-23. doi: 10.3892/ijo.29.3.615. Int J Oncol. 2006. PMID: 16865277

10

Growth inhibition and induction of apoptosis in acute myeloid leukemia cells by new indolinone derivatives targeting fibroblast growth factor, platelet-derived growth factor, and vascular endothelial growth factor receptors.

Kulimova E, Oelmann E, Bisping G, Kienast J, Mesters RM, Schwäble J, Hilberg F, Roth GJ, Munzert G, Stefanic M, Steffen B, Brandts C, Müller-Tidow C, Kolkmeyer A, Büchner T, Serve H, Berdel WE. Kulimova E, et al. Among authors: brandts c. Mol Cancer Ther. 2006 Dec;5(12):3105-12. doi: 10.1158/1535-7163.MCT-06-0323. Mol Cancer Ther. 2006. PMID: 17172413

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