Karle C - Search Results

1

Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells.

Karle C, Gehrig T, Wodopia R, Höschele S, Kreye VA, Katus HA, Bärtsch P, Mairbäurl H. Karle C, et al. Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1154-60. doi: 10.1152/ajplung.00403.2002. Epub 2004 Jan 16. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 14729515 Free article.

2

K+ channel activation with minoxidil stimulates nasal-epithelial ion transport and blunts exaggerated hypoxic pulmonary hypertension.

Peth S, Karle C, Dehnert C, Bärtsch P, Mairbäurl H. Peth S, et al. Among authors: karle c. High Alt Med Biol. 2006 Spring;7(1):54-63. doi: 10.1089/ham.2006.7.54. High Alt Med Biol. 2006. PMID: 16544967 Clinical Trial.

3

Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line.

Wei Z, Thomas D, Karle CA, Kathöfer S, Schenkel J, Kreye VA, Ficker E, Wible BA, Kiehn J. Wei Z, et al. Chin Med J (Engl). 2002 May;115(5):668-76. Chin Med J (Engl). 2002. PMID: 12133532

4

The antipsychotic drug chlorpromazine inhibits HERG potassium channels.

Thomas D, Wu K, Kathöfer S, Katus HA, Schoels W, Kiehn J, Karle CA. Thomas D, et al. Br J Pharmacol. 2003 Jun;139(3):567-74. doi: 10.1038/sj.bjp.0705283. Br J Pharmacol. 2003. PMID: 12788816 Free PMC article.

5

Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels.

Thomas D, Kathofer S, Zhang W, Wu K, Wimmer AB, Zitron E, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J. Thomas D, et al. Br J Pharmacol. 2003 Nov;140(5):996-1002. doi: 10.1038/sj.bjp.0705502. Epub 2003 Sep 29. Br J Pharmacol. 2003. PMID: 14517175 Free PMC article.

6

Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.

Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA. Scholz EP, et al. Among authors: karle ca. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. doi: 10.1007/s00210-003-0805-5. Epub 2003 Oct 14. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14557918

7

Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.

Thomas D, Hammerling BC, Wu K, Wimmer AB, Ficker EK, Kirsch GE, Kochan MC, Wible BA, Scholz EP, Zitron E, Kathöfer S, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J. Thomas D, et al. Among authors: karle ca. Br J Pharmacol. 2004 Jun;142(3):485-94. doi: 10.1038/sj.bjp.0705795. Epub 2004 May 17. Br J Pharmacol. 2004. PMID: 15148258 Free PMC article.

8

Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A.

Zitron E, Kiesecker C, Lück S, Kathöfer S, Thomas D, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA. Zitron E, et al. Among authors: karle ca. Cardiovasc Res. 2004 Aug 15;63(3):520-7. doi: 10.1016/j.cardiores.2004.02.015. Cardiovasc Res. 2004. PMID: 15276477

9

Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone.

Zitron E, Kiesecker C, Scholz E, Lück S, Bloehs R, Kathöfer S, Thomas D, Kiehn J, Kreye VA, Katus HA, Schoels W, Karle CA. Zitron E, et al. Among authors: karle ca. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):146-56. doi: 10.1007/s00210-004-0952-3. Epub 2004 Jul 29. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15322737

10

Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors.

Thomas D, Wu K, Wimmer AB, Zitron E, Hammerling BC, Kathöfer S, Lueck S, Bloehs R, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA. Thomas D, et al. Among authors: karle ca. J Mol Med (Berl). 2004 Dec;82(12):826-37. doi: 10.1007/s00109-004-0582-8. Epub 2004 Sep 8. J Mol Med (Berl). 2004. PMID: 15365637

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