Martin SW - Search Results

1

Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.

Poindexter GS, Bruce MA, Breitenbucher JG, Higgins MA, Sit SY, Romine JL, Martin SW, Ward SA, McGovern RT, Clarke W, Russell J, Antal-Zimanyi I. Poindexter GS, et al. Among authors: martin sw. Bioorg Med Chem. 2004 Jan 15;12(2):507-21. doi: 10.1016/j.bmc.2003.10.016. Bioorg Med Chem. 2004. PMID: 14723969

2

Nonprostanoid prostacyclin mimetics. 5. Structure-activity relationships associated with [3-[4-(4,5-diphenyl-2-oxazolyl)-5- oxazolyl]phenoxy]acetic acid.

Meanwell NA, Romine JL, Rosenfeld MJ, Martin SW, Trehan AK, Wright JJ, Malley MF, Gougoutas JZ, Brassard CL, Buchanan JO, et al. Meanwell NA, et al. Among authors: martin sw. J Med Chem. 1993 Nov 26;36(24):3884-903. doi: 10.1021/jm00076a018. J Med Chem. 1993. PMID: 7504734

3

Dihydropyridine neuropeptide Y Y(1) receptor antagonists.

Poindexter GS, Bruce MA, LeBoulluec KL, Monkovic I, Martin SW, Parker EM, Iben LG, McGovern RT, Ortiz AA, Stanley JA, Mattson GK, Kozlowski M, Arcuri M, Antal-Zimanyi I. Poindexter GS, et al. Among authors: martin sw. Bioorg Med Chem Lett. 2002 Feb 11;12(3):379-82. doi: 10.1016/s0960-894x(01)00761-2. Bioorg Med Chem Lett. 2002. PMID: 11814801

4

4,5-diphenyltriazol-3-ones: openers of large-conductance Ca(2+)-activated potassium (maxi-K) channels.

Romine JL, Martin SW, Gribkoff VK, Boissard CG, Dworetzky SI, Natale J, Li Y, Gao Q, Meanwell NA, Starrett JE Jr. Romine JL, et al. Among authors: martin sw. J Med Chem. 2002 Jul 4;45(14):2942-52. doi: 10.1021/jm010569q. J Med Chem. 2002. PMID: 12086481

5

Novel openers of Ca2+-dependent large-conductance potassium channels: symmetrical pharmacophore and electrophysiological evaluation of bisphenols.

Li Y, Johnson G, Romine JL, Meanwell NA, Martin SW, Dworetzky SI, Boissard CG, Gribkoff VK, Starrett JE Jr. Li Y, et al. Among authors: martin sw. Bioorg Med Chem Lett. 2003 Apr 17;13(8):1437-9. doi: 10.1016/s0960-894x(03)00156-2. Bioorg Med Chem Lett. 2003. PMID: 12668007

6

Application of solution-phase parallel synthesis to preparation of trisubstituted 1,2,4-triazoles.

Martin SW, Romine JL, Chen L, Mattson G, Antal-Zimanyi IA, Poindexter GS. Martin SW, et al. J Comb Chem. 2004 Jan-Feb;6(1):35-7. doi: 10.1021/cc034018s. J Comb Chem. 2004. PMID: 14714981 No abstract available.

7

3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR.

Romine JL, Martin SW, Meanwell NA, Gribkoff VK, Boissard CG, Dworetzky SI, Natale J, Moon S, Ortiz A, Yeleswaram S, Pajor L, Gao Q, Starrett JE Jr. Romine JL, et al. Among authors: martin sw. J Med Chem. 2007 Feb 8;50(3):528-42. doi: 10.1021/jm061006n. J Med Chem. 2007. PMID: 17266205

8

Identification of hepatitis C virus NS5A inhibitors.

Lemm JA, O'Boyle D 2nd, Liu M, Nower PT, Colonno R, Deshpande MS, Snyder LB, Martin SW, St Laurent DR, Serrano-Wu MH, Romine JL, Meanwell NA, Gao M. Lemm JA, et al. Among authors: martin sw. J Virol. 2010 Jan;84(1):482-91. doi: 10.1128/JVI.01360-09. J Virol. 2010. PMID: 19812153 Free PMC article.

9

Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus.

Zheng X, Hudyma TW, Martin SW, Bergstrom C, Ding M, He F, Romine J, Poss MA, Kadow JF, Chang CH, Wan J, Witmer MR, Morin P, Camac DM, Sheriff S, Beno BR, Rigat KL, Wang YK, Fridell R, Lemm J, Qiu D, Liu M, Voss S, Pelosi L, Roberts SB, Gao M, Knipe J, Gentles RG. Zheng X, et al. Among authors: martin sw. Bioorg Med Chem Lett. 2011 May 15;21(10):2925-9. doi: 10.1016/j.bmcl.2011.03.067. Epub 2011 Mar 23. Bioorg Med Chem Lett. 2011. PMID: 21486696

10

The synthesis and evaluation of a novel class of (E)-3-(1-cyclohexyl-1H-pyrazol-3-yl)-2-methylacrylic acid hepatitis C virus polymerase NS5B inhibitors.

Martin SW, Glunz P, Beno BR, Bergstrom C, Romine JL, Priestley ES, Newman M, Gao M, Roberts S, Rigat K, Fridell R, Qiu D, Knobloh G, Wang YK. Martin SW, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):2869-72. doi: 10.1016/j.bmcl.2011.03.086. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21507645

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