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Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis.
Oerlemans R, Vink J, Dijkmans BA, Assaraf YG, van Miltenburg M, van der Heijden J, Ifergan I, Lems WF, Scheper RJ, Kaspers GJ, Cloos J, Jansen G. Oerlemans R, et al. Ann Rheum Dis. 2007 Oct;66(10):1289-95. doi: 10.1136/ard.2006.060509. Epub 2007 Jan 31. Ann Rheum Dis. 2007. PMID: 17267514 Free PMC article.
Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide.
van der Heijden JW, Oerlemans R, Tak PP, Assaraf YG, Kraan MC, Scheffer GL, van der Laken CJ, Lems WF, Scheper RJ, Dijkmans BA, Jansen G. van der Heijden JW, et al. Among authors: oerlemans r. Arthritis Rheum. 2009 Mar;60(3):669-77. doi: 10.1002/art.24354. Arthritis Rheum. 2009. PMID: 19248091 Free article.
Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFalpha.
van der Heijden J, de Jong MC, Dijkmans BA, Lems WF, Oerlemans R, Kathmann I, Schalkwijk CG, Scheffer GL, Scheper RJ, Jansen G. van der Heijden J, et al. Among authors: oerlemans r. Ann Rheum Dis. 2004 Feb;63(2):138-43. doi: 10.1136/ard.2002.005249. Ann Rheum Dis. 2004. PMID: 14722201 Free PMC article.
Sulfasalazine down-regulates the expression of the angiogenic factors platelet-derived endothelial cell growth factor/thymidine phosphorylase and interleukin-8 in human monocytic-macrophage THP1 and U937 cells.
de Bruin M, Peters GJ, Oerlemans R, Assaraf YG, Masterson AJ, Adema AD, Dijkmans BA, Pinedo HM, Jansen G. de Bruin M, et al. Among authors: oerlemans r. Mol Pharmacol. 2004 Oct;66(4):1054-60. doi: 10.1124/mol.104.000315. Epub 2004 Jul 21. Mol Pharmacol. 2004. PMID: 15269287
Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein.
Oerlemans R, Franke NE, Assaraf YG, Cloos J, van Zantwijk I, Berkers CR, Scheffer GL, Debipersad K, Vojtekova K, Lemos C, van der Heijden JW, Ylstra B, Peters GJ, Kaspers GL, Dijkmans BA, Scheper RJ, Jansen G. Oerlemans R, et al. Blood. 2008 Sep 15;112(6):2489-99. doi: 10.1182/blood-2007-08-104950. Epub 2008 Jun 18. Blood. 2008. PMID: 18565852 Free article.
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration.
van de Ven R, Scheffer GL, Reurs AW, Lindenberg JJ, Oerlemans R, Jansen G, Gillet JP, Glasgow JN, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. van de Ven R, et al. Among authors: oerlemans r. Blood. 2008 Sep 15;112(6):2353-9. doi: 10.1182/blood-2008-03-147850. Epub 2008 Jul 14. Blood. 2008. PMID: 18625884 Free PMC article.
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