Parren PW - Search Results

1

Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.

Saphire EO, Stanfield RL, Crispin MD, Morris G, Zwick MB, Pantophlet RA, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Saphire EO, et al. Among authors: parren pw. Adv Exp Med Biol. 2003;535:55-66. doi: 10.1007/978-1-4615-0065-0_4. Adv Exp Med Biol. 2003. PMID: 14714888 Review. No abstract available.

2

Contrasting IgG structures reveal extreme asymmetry and flexibility.

Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Saphire EO, et al. Among authors: parren pw. J Mol Biol. 2002 May 24;319(1):9-18. doi: 10.1016/S0022-2836(02)00244-9. J Mol Biol. 2002. PMID: 12051932

3

Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.

Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA. Saphire EO, et al. Among authors: parren pw. J Mol Biol. 2007 Jun 8;369(3):696-709. doi: 10.1016/j.jmb.2007.01.060. Epub 2007 Jan 27. J Mol Biol. 2007. PMID: 17445828 Free PMC article.

4

Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1.

Saphire EO, Parren PW, Barbas CF 3rd, Burton DR, Wilson IA. Saphire EO, et al. Among authors: parren pw. Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):168-71. doi: 10.1107/s0907444900017376. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11134947

5

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, Wilson IA. Saphire EO, et al. Among authors: parren pw. Science. 2001 Aug 10;293(5532):1155-9. doi: 10.1126/science.1061692. Science. 2001. PMID: 11498595

6

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

Pantophlet R, Ollmann Saphire E, Poignard P, Parren PW, Wilson IA, Burton DR. Pantophlet R, et al. Among authors: parren pw. J Virol. 2003 Jan;77(1):642-58. doi: 10.1128/jvi.77.1.642-658.2003. J Virol. 2003. PMID: 12477867 Free PMC article.

7

Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.

Zwick MB, Parren PW, Saphire EO, Church S, Wang M, Scott JK, Dawson PE, Wilson IA, Burton DR. Zwick MB, et al. Among authors: parren pw. J Virol. 2003 May;77(10):5863-76. doi: 10.1128/jvi.77.10.5863-5876.2003. J Virol. 2003. PMID: 12719580 Free PMC article.

8

A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.

Zwick MB, Kelleher R, Jensen R, Labrijn AF, Wang M, Quinnan GV Jr, Parren PW, Burton DR. Zwick MB, et al. Among authors: parren pw. J Virol. 2003 Jun;77(12):6965-78. doi: 10.1128/jvi.77.12.6965-6978.2003. J Virol. 2003. PMID: 12768015 Free PMC article.

9

The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5.

Zwick MB, Komori HK, Stanfield RL, Church S, Wang M, Parren PW, Kunert R, Katinger H, Wilson IA, Burton DR. Zwick MB, et al. Among authors: parren pw. J Virol. 2004 Mar;78(6):3155-61. doi: 10.1128/jvi.78.6.3155-3161.2004. J Virol. 2004. PMID: 14990736 Free PMC article.

10

Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.

Zwick MB, Wang M, Poignard P, Stiegler G, Katinger H, Burton DR, Parren PW. Zwick MB, et al. Among authors: parren pw. J Virol. 2001 Dec;75(24):12198-208. doi: 10.1128/JVI.75.24.12198-12208.2001. J Virol. 2001. PMID: 11711611 Free PMC article.

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