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Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma.
Vanharanta S, Buchta M, McWhinney SR, Virta SK, Peçzkowska M, Morrison CD, Lehtonen R, Januszewicz A, Järvinen H, Juhola M, Mecklin JP, Pukkala E, Herva R, Kiuru M, Nupponen NN, Aaltonen LA, Neumann HP, Eng C. Vanharanta S, et al. Am J Hum Genet. 2004 Jan;74(1):153-9. doi: 10.1086/381054. Epub 2003 Dec 18. Am J Hum Genet. 2004. PMID: 14685938 Free PMC article.
Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors.
Lehtonen R, Kiuru M, Vanharanta S, Sjöberg J, Aaltonen LM, Aittomäki K, Arola J, Butzow R, Eng C, Husgafvel-Pursiainen K, Isola J, Järvinen H, Koivisto P, Mecklin JP, Peltomäki P, Salovaara R, Wasenius VM, Karhu A, Launonen V, Nupponen NN, Aaltonen LA. Lehtonen R, et al. Among authors: vanharanta s. Am J Pathol. 2004 Jan;164(1):17-22. doi: 10.1016/S0002-9440(10)63091-X. Am J Pathol. 2004. PMID: 14695314 Free PMC article.
7q deletion mapping and expression profiling in uterine fibroids.
Vanharanta S, Wortham NC, Laiho P, Sjöberg J, Aittomäki K, Arola J, Tomlinson IP, Karhu A, Arango D, Aaltonen LA. Vanharanta S, et al. Oncogene. 2005 Sep 29;24(43):6545-54. doi: 10.1038/sj.onc.1208784. Oncogene. 2005. PMID: 15940248
Distinct expression profile in fumarate-hydratase-deficient uterine fibroids.
Vanharanta S, Pollard PJ, Lehtonen HJ, Laiho P, Sjöberg J, Leminen A, Aittomäki K, Arola J, Kruhoffer M, Orntoft TF, Tomlinson IP, Kiuru M, Arango D, Aaltonen LA. Vanharanta S, et al. Hum Mol Genet. 2006 Jan 1;15(1):97-103. doi: 10.1093/hmg/ddi431. Epub 2005 Nov 30. Hum Mol Genet. 2006. PMID: 16319128
Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis.
Laiho P, Kokko A, Vanharanta S, Salovaara R, Sammalkorpi H, Järvinen H, Mecklin JP, Karttunen TJ, Tuppurainen K, Davalos V, Schwartz S Jr, Arango D, Mäkinen MJ, Aaltonen LA. Laiho P, et al. Among authors: vanharanta s. Oncogene. 2007 Jan 11;26(2):312-20. doi: 10.1038/sj.onc.1209778. Epub 2006 Jul 3. Oncogene. 2007. PMID: 16819509
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.
Petrova TV, Nykänen A, Norrmén C, Ivanov KI, Andersson LC, Haglund C, Puolakkainen P, Wempe F, von Melchner H, Gradwohl G, Vanharanta S, Aaltonen LA, Saharinen J, Gentile M, Clarke A, Taipale J, Oliver G, Alitalo K. Petrova TV, et al. Among authors: vanharanta s. Cancer Cell. 2008 May;13(5):407-19. doi: 10.1016/j.ccr.2008.02.020. Cancer Cell. 2008. PMID: 18455124 Free article.
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