Schunack W - Search Results

1

Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists.

Govoni M, Bakker RA, van de Wetering I, Smit MJ, Menge WM, Timmerman H, Elz S, Schunack W, Leurs R. Govoni M, et al. Among authors: schunack w. J Med Chem. 2003 Dec 18;46(26):5812-24. doi: 10.1021/jm030936t. J Med Chem. 2003. PMID: 14667234

2

Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.

Bruysters M, Pertz HH, Teunissen A, Bakker RA, Gillard M, Chatelain P, Schunack W, Timmerman H, Leurs R. Bruysters M, et al. Among authors: schunack w. Eur J Pharmacol. 2004 Mar 8;487(1-3):55-63. doi: 10.1016/j.ejphar.2004.01.028. Eur J Pharmacol. 2004. PMID: 15033376

3

Structure-activity relationships of histamine H1-receptor agonists.

Pertz HH, Elz S, Schunack W. Pertz HH, et al. Among authors: schunack w. Mini Rev Med Chem. 2004 Nov;4(9):935-40. doi: 10.2174/1389557043403198. Mini Rev Med Chem. 2004. PMID: 15544554 Review.

4

Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties.

Sasse A, Ligneau X, Rouleau A, Elz S, Ganellin CR, Arrang JM, Schwartz JC, Schunack W, Stark H. Sasse A, et al. Among authors: schunack w. J Med Chem. 2002 Aug 29;45(18):4000-10. doi: 10.1021/jm020910m. J Med Chem. 2002. PMID: 12190321

5

N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.

Menghin S, Pertz HH, Kramer K, Seifert R, Schunack W, Elz S. Menghin S, et al. Among authors: schunack w. J Med Chem. 2003 Dec 4;46(25):5458-70. doi: 10.1021/jm0309147. J Med Chem. 2003. PMID: 14640554

6

Synthesis and histamine H1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues.

Leschke C, Elz S, Garbarg M, Schunack W. Leschke C, et al. Among authors: schunack w. J Med Chem. 1995 Apr 14;38(8):1287-94. doi: 10.1021/jm00008a007. J Med Chem. 1995. PMID: 7731015

7

N alpha-alkylated derivatives of 2-phenylhistamines: synthesis and in vitro activity of potent histamine H1-receptor agonists.

Kramer K, Elz S, Pertz HH, Schunack W. Kramer K, et al. Among authors: schunack w. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2583-8. doi: 10.1016/s0960-894x(98)00461-2. Bioorg Med Chem Lett. 1998. PMID: 9873585

8

Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity.

Sasse A, Stark H, Reidemeister S, Hüls A, Elz S, Ligneau X, Ganellin CR, Schwartz JC, Schunack W. Sasse A, et al. Among authors: schunack w. J Med Chem. 1999 Oct 7;42(20):4269-74. doi: 10.1021/jm991068w. J Med Chem. 1999. PMID: 10514298

9

Radiosynthesis and biodistribution of 123I-labeled antagonists of the histamine H3 receptor as potential SPECT ligands.

Windhorst AD, Timmerman H, Klok RP, Custers FG, Menge WM, Leurs R, Stark H, Schunack W, Gielen EG, van Kroonenburgh MJ, Herscheid JD. Windhorst AD, et al. Among authors: schunack w. Nucl Med Biol. 1999 Aug;26(6):651-9. doi: 10.1016/s0969-8051(99)00014-1. Nucl Med Biol. 1999. PMID: 10587103

10

Ring-substituted histaprodifen analogues as partial agonists for histamine H(1) receptors: synthesis and structure-activity relationships.

Elz S, Kramer K, Leschke C, Schunack W. Elz S, et al. Among authors: schunack w. Eur J Med Chem. 2000 Jan;35(1):41-52. doi: 10.1016/s0223-5234(00)00105-7. Eur J Med Chem. 2000. PMID: 10733602

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