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A novel formulation of inhaled doxycycline reduces allergen-induced inflammation, hyperresponsiveness and remodeling by matrix metalloproteinases and cytokines modulation in a mouse model of asthma.
Gueders MM, Bertholet P, Perin F, Rocks N, Maree R, Botta V, Louis R, Foidart JM, Noel A, Evrard B, Cataldo DD. Gueders MM, et al. Biochem Pharmacol. 2008 Jan 15;75(2):514-26. doi: 10.1016/j.bcp.2007.09.012. Epub 2007 Sep 18. Biochem Pharmacol. 2008. PMID: 17950252 Free article.
Role of ADAM and ADAMTS metalloproteinases in airway diseases.
Paulissen G, Rocks N, Gueders MM, Crahay C, Quesada-Calvo F, Bekaert S, Hacha J, El Hour M, Foidart JM, Noel A, Cataldo DD. Paulissen G, et al. Among authors: gueders mm. Respir Res. 2009 Dec 24;10(1):127. doi: 10.1186/1465-9921-10-127. Respir Res. 2009. PMID: 20034386 Free PMC article. Review.
ADAM-8, a metalloproteinase, drives acute allergen-induced airway inflammation.
Paulissen G, Rocks N, Guéders MM, Bedoret D, Crahay C, Quesada-Calvo F, Hacha J, Bekaert S, Desmet C, Foidart JM, Bureau F, Noel A, Cataldo DD. Paulissen G, et al. Among authors: gueders mm. Eur J Immunol. 2011 Feb;41(2):380-91. doi: 10.1002/eji.200940286. Epub 2010 Dec 29. Eur J Immunol. 2011. PMID: 21268008 Free article.
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