Beuming T - Search Results

1

Probing conformational changes in neurotransmitter transporters: a structural context.

Goldberg NR, Beuming T, Soyer OS, Goldstein RA, Weinstein H, Javitch JA. Goldberg NR, et al. Among authors: beuming t. Eur J Pharmacol. 2003 Oct 31;479(1-3):3-12. doi: 10.1016/j.ejphar.2003.08.052. Eur J Pharmacol. 2003. PMID: 14612133 Review.

2

State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.

Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. Quick M, et al. Among authors: beuming t. J Biol Chem. 2006 Sep 8;281(36):26444-54. doi: 10.1074/jbc.M602438200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798738 Free article.

3

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function.

Beuming T, Shi L, Javitch JA, Weinstein H. Beuming T, et al. Mol Pharmacol. 2006 Nov;70(5):1630-42. doi: 10.1124/mol.106.026120. Epub 2006 Jul 31. Mol Pharmacol. 2006. PMID: 16880288

4

Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation.

Dehnes Y, Shan J, Beuming T, Shi L, Weinstein H, Javitch JA. Dehnes Y, et al. Among authors: beuming t. Neurochem Int. 2014 Jul;73:4-15. doi: 10.1016/j.neuint.2014.02.003. Epub 2014 Feb 24. Neurochem Int. 2014. PMID: 24576496 Free PMC article.

5

A knowledge-based scale for the analysis and prediction of buried and exposed faces of transmembrane domain proteins.

Beuming T, Weinstein H. Beuming T, et al. Bioinformatics. 2004 Aug 12;20(12):1822-35. doi: 10.1093/bioinformatics/bth143. Epub 2004 Feb 26. Bioinformatics. 2004. PMID: 14988128

6

Modeling membrane proteins based on low-resolution electron microscopy maps: a template for the TM domains of the oxalate transporter OxlT.

Beuming T, Weinstein H. Beuming T, et al. Protein Eng Des Sel. 2005 Mar;18(3):119-25. doi: 10.1093/protein/gzi013. Epub 2005 Apr 8. Protein Eng Des Sel. 2005. PMID: 15820982

7

A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.

Sen N, Shi L, Beuming T, Weinstein H, Javitch JA. Sen N, et al. Among authors: beuming t. Neuropharmacology. 2005 Nov;49(6):780-90. doi: 10.1016/j.neuropharm.2005.08.014. Epub 2005 Oct 10. Neuropharmacology. 2005. PMID: 16216288

8

The binding sites for cocaine and dopamine in the dopamine transporter overlap.

Beuming T, Kniazeff J, Bergmann ML, Shi L, Gracia L, Raniszewska K, Newman AH, Javitch JA, Weinstein H, Gether U, Loland CJ. Beuming T, et al. Nat Neurosci. 2008 Jul;11(7):780-9. doi: 10.1038/nn.2146. Epub 2008 Jun 22. Nat Neurosci. 2008. PMID: 18568020 Free PMC article.

9

A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors.

Michino M, Donthamsetti P, Beuming T, Banala A, Duan L, Roux T, Han Y, Trinquet E, Newman AH, Javitch JA, Shi L. Michino M, et al. Among authors: beuming t. Mol Pharmacol. 2013 Dec;84(6):854-64. doi: 10.1124/mol.113.087833. Epub 2013 Sep 23. Mol Pharmacol. 2013. PMID: 24061855 Free PMC article.

10

What can crystal structures of aminergic receptors tell us about designing subtype-selective ligands?

Michino M, Beuming T, Donthamsetti P, Newman AH, Javitch JA, Shi L. Michino M, et al. Among authors: beuming t. Pharmacol Rev. 2015;67(1):198-213. doi: 10.1124/pr.114.009944. Pharmacol Rev. 2015. PMID: 25527701 Free PMC article. Review.

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