Eikel D - Search Results

1

Liposomal daunorubicin (DaunoXome) in multiple myeloma: a modified VAD regimen using short-term infusion.

Eucker J, Eikel D, Heider U, Jakob C, Zavrski I, Gatz F, Mergenthaler HG, Jungclas H, Possinger K, Sezer O. Eucker J, et al. Among authors: eikel d. Anticancer Drugs. 2003 Nov;14(10):793-9. doi: 10.1097/00001813-200311000-00004. Anticancer Drugs. 2003. PMID: 14597873 Clinical Trial.

2

Novel valproic acid derivatives with hemoglobin F inducing activity.

Rönndahl G, Mönkemeyer S, Schulze S, Pekrun A, Eikel D, Nau H, Witt O. Rönndahl G, et al. Among authors: eikel d. Am J Hematol. 2006 May;81(5):374-6. doi: 10.1002/ajh.20575. Am J Hematol. 2006. PMID: 16628726 Free article.

3

Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.

Deubzer H, Busche B, Rönndahl G, Eikel D, Michaelis M, Cinatl J, Schulze S, Nau H, Witt O. Deubzer H, et al. Among authors: eikel d. Leuk Res. 2006 Sep;30(9):1167-75. doi: 10.1016/j.leukres.2006.01.009. Epub 2006 Feb 28. Leuk Res. 2006. PMID: 16510182

4

Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid.

Michaelis M, Köhler N, Reinisch A, Eikel D, Gravemann U, Doerr HW, Nau H, Cinatl J Jr. Michaelis M, et al. Among authors: eikel d. Biochem Pharmacol. 2004 Aug 1;68(3):531-8. doi: 10.1016/j.bcp.2004.04.013. Biochem Pharmacol. 2004. PMID: 15242819

5

Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives.

Eikel D, Lampen A, Nau H. Eikel D, et al. Chem Res Toxicol. 2006 Feb;19(2):272-8. doi: 10.1021/tx0502241. Chem Res Toxicol. 2006. PMID: 16485903

6

S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides.

Eikel D, Hoffmann K, Zoll K, Lampen A, Nau H. Eikel D, et al. Drug Metab Dispos. 2006 Apr;34(4):612-20. doi: 10.1124/dmd.105.008078. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415118

7

Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.

Eickholt BJ, Towers GJ, Ryves WJ, Eikel D, Adley K, Ylinen LM, Chadborn NH, Harwood AJ, Nau H, Williams RS. Eickholt BJ, et al. Among authors: eikel d. Mol Pharmacol. 2005 May;67(5):1426-33. doi: 10.1124/mol.104.009308. Epub 2005 Feb 1. Mol Pharmacol. 2005. PMID: 15687223 Free PMC article.

8

Valproic acid induces extracellular signal-regulated kinase 1/2 activation and inhibits apoptosis in endothelial cells.

Michaelis M, Suhan T, Michaelis UR, Beek K, Rothweiler F, Tausch L, Werz O, Eikel D, Zörnig M, Nau H, Fleming I, Doerr HW, Cinatl J Jr. Michaelis M, et al. Among authors: eikel d. Cell Death Differ. 2006 Mar;13(3):446-53. doi: 10.1038/sj.cdd.4401759. Cell Death Differ. 2006. PMID: 16167071

9

The embryonic stem cell test as tool to assess structure-dependent teratogenicity: the case of valproic acid.

Riebeling C, Pirow R, Becker K, Buesen R, Eikel D, Kaltenhäuser J, Meyer F, Nau H, Slawik B, Visan A, Volland J, Spielmann H, Luch A, Seiler A. Riebeling C, et al. Among authors: eikel d. Toxicol Sci. 2011 Apr;120(2):360-70. doi: 10.1093/toxsci/kfr001. Epub 2011 Jan 11. Toxicol Sci. 2011. PMID: 21227905 Free PMC article.

10

Increased replication of human cytomegalovirus in retinal pigment epithelial cells by valproic acid depends on histone deacetylase inhibition.

Michaelis M, Suhan T, Reinisch A, Reisenauer A, Fleckenstein C, Eikel D, Gümbel H, Doerr HW, Nau H, Cinatl J Jr. Michaelis M, et al. Among authors: eikel d. Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3451-7. doi: 10.1167/iovs.05-0369. Invest Ophthalmol Vis Sci. 2005. PMID: 16123451

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