O'Rahilly S - Search Results

1

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.

Barroso I, Luan J, Middelberg RP, Harding AH, Franks PW, Jakes RW, Clayton D, Schafer AJ, O'Rahilly S, Wareham NJ. Barroso I, et al. PLoS Biol. 2003 Oct;1(1):E20. doi: 10.1371/journal.pbio.0000020. Epub 2003 Oct 13. PLoS Biol. 2003. PMID: 14551916 Free PMC article.

2

Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10.

Franks PW, Bhattacharyya S, Luan J, Montague C, Brennand J, Challis B, Brage S, Ekelund U, Middelberg RP, O'Rahilly S, Wareham NJ. Franks PW, et al. Hypertension. 2004 Feb;43(2):224-8. doi: 10.1161/01.HYP.0000109319.63240.08. Epub 2003 Dec 22. Hypertension. 2004. PMID: 14691196

3

Genetic factors in type 2 diabetes: the end of the beginning?

O'Rahilly S, Barroso I, Wareham NJ. O'Rahilly S, et al. Science. 2005 Jan 21;307(5708):370-3. doi: 10.1126/science.1104346. Science. 2005. PMID: 15662000

4

Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance.

Franks PW, Luan J, Barroso I, Brage S, Gonzalez Sanchez JL, Ekelund U, Ríos MS, Schafer AJ, O'Rahilly S, Wareham NJ. Franks PW, et al. Diabetes. 2005 Sep;54(9):2795-801. doi: 10.2337/diabetes.54.9.2795. Diabetes. 2005. PMID: 16123371

5

Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.

Barroso I, Luan J, Sandhu MS, Franks PW, Crowley V, Schafer AJ, O'Rahilly S, Wareham NJ. Barroso I, et al. Diabetologia. 2006 Mar;49(3):501-5. doi: 10.1007/s00125-005-0130-2. Epub 2006 Jan 25. Diabetologia. 2006. PMID: 16435105

6

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.

Harding AH, Loos RJ, Luan J, O'Rahilly S, Wareham NJ, Barroso I. Harding AH, et al. Diabetologia. 2006 Nov;49(11):2642-8. doi: 10.1007/s00125-006-0430-1. Epub 2006 Sep 20. Diabetologia. 2006. PMID: 17019602 Free PMC article.

7

Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.

Collins SC, Luan J, Thompson AJ, Daly A, Semple RK, O'Rahilly S, Wareham NJ, Barroso I. Collins SC, et al. Diabetologia. 2007 Mar;50(3):555-62. doi: 10.1007/s00125-006-0534-7. Epub 2007 Jan 10. Diabetologia. 2007. PMID: 17216283 Free PMC article.

8

Digenic inheritance of severe insulin resistance in a human pedigree.

Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, Meirhaeghe A, Harding AH, Ihrke G, Rajanayagam O, Soos MA, George S, Berger D, Thomas EL, Bell JD, Meeran K, Ross RJ, Vidal-Puig A, Wareham NJ, O'Rahilly S, Chatterjee VK, Schafer AJ. Savage DB, et al. Nat Genet. 2002 Aug;31(4):379-84. doi: 10.1038/ng926. Epub 2002 Jul 15. Nat Genet. 2002. PMID: 12118251

9

A family with severe insulin resistance and diabetes due to a mutation in AKT2.

George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC, Soos MA, Murgatroyd PR, Williams RM, Acerini CL, Dunger DB, Barford D, Umpleby AM, Wareham NJ, Davies HA, Schafer AJ, Stoffel M, O'Rahilly S, Barroso I. George S, et al. Science. 2004 May 28;304(5675):1325-8. doi: 10.1126/science.1096706. Science. 2004. PMID: 15166380 Free PMC article.

10

The changing classification and diagnosis of diabetes. New classification is based on pathogenesis, not insulin dependence.

Wareham NJ, O'Rahilly S. Wareham NJ, et al. BMJ. 1998 Aug 8;317(7155):359-60. doi: 10.1136/bmj.317.7155.359. BMJ. 1998. PMID: 9694745 Free PMC article. No abstract available.

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