Shi J - Search Results

1

Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase.

Ray AS, Schinazi RF, Murakami E, Basavapathruni A, Shi J, Zorca SM, Chu CK, Anderson KS. Ray AS, et al. Among authors: shi j. Antivir Chem Chemother. 2003 May;14(3):115-25. doi: 10.1177/095632020301400301. Antivir Chem Chemother. 2003. PMID: 14521328 Free article. Review.

2

Insights into the molecular mechanism of inhibition and drug resistance for HIV-1 RT with carbovir triphosphate.

Ray AS, Yang Z, Shi J, Hobbs A, Schinazi RF, Chu CK, Anderson KS. Ray AS, et al. Among authors: shi j. Biochemistry. 2002 Apr 23;41(16):5150-62. doi: 10.1021/bi0121858. Biochemistry. 2002. PMID: 11955063

3

Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase.

Ray AS, Murakami E, Peterson CN, Shi J, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: shi j. Antiviral Res. 2002 Dec;56(3):189-205. doi: 10.1016/s0166-3542(02)00102-x. Antiviral Res. 2002. PMID: 12406504

4

Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP.

Feng JY, Shi J, Schinazi RF, Anderson KS. Feng JY, et al. Among authors: shi j. FASEB J. 1999 Sep;13(12):1511-7. doi: 10.1096/fasebj.13.12.1511. FASEB J. 1999. PMID: 10463941

5

N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.

Shi J, Mathew JS, Tharnish PM, Rachakonda S, Pai SB, Adams M, Grier JP, Gallagher K, Zhang H, Wu JT, Shi G, Geleziunas R, Erickson-Viitanen S, Stuyver L, Otto MJ, Watanabe KA, Schinazi RF. Shi J, et al. Among authors: shi g. Antivir Chem Chemother. 2003 Mar;14(2):81-90. doi: 10.1177/095632020301400203. Antivir Chem Chemother. 2003. PMID: 12856919 Free article.

6

Synthesis of beta-enantiomers of N4-hydroxy-3'-deoxypyrimidine nucleosides and their evaluation against bovine viral diarrhoea virus and hepatitis C virus in cell culture.

Hollecker L, Choo H, Chong Y, Chu CK, Lostia S, McBrayer TR, Stuyver LJ, Mason JC, Du J, Rachakonda S, Shi J, Schinazi RF, Watanabe KA. Hollecker L, et al. Among authors: shi j. Antivir Chem Chemother. 2004 Jan;15(1):43-55. doi: 10.1177/095632020401500105. Antivir Chem Chemother. 2004. PMID: 15074714 Free article.

7

2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions.

Shi J, Ray AS, Mathew JS, Anderson KS, Chu CK, Schinazi RF. Shi J, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2159-62. doi: 10.1016/j.bmcl.2004.02.031. Bioorg Med Chem Lett. 2004. PMID: 15081000

8

Characterization of hepatitis B virus inhibition by novel 2'-fluoro-2',3'-unsaturated beta-D- and L-nucleosides.

Pai SB, Pai RB, Xie MY, Beker T, Shi J, Tharnish PM, Chu CK, Schinazi RF. Pai SB, et al. Among authors: shi j. Antivir Chem Chemother. 2005;16(3):183-92. doi: 10.1177/095632020501600304. Antivir Chem Chemother. 2005. PMID: 16004081 Free article.

9

Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.

Shi J, McAtee JJ, Schlueter Wirtz S, Tharnish P, Juodawlkis A, Liotta DC, Schinazi RF. Shi J, et al. J Med Chem. 1999 Mar 11;42(5):859-67. doi: 10.1021/jm980510s. J Med Chem. 1999. PMID: 10072683

10

Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides.

Shi J, Du J, Ma T, Pankiewicz KW, Patterson SE, Hassan AE, Tharnish PM, McBrayer TR, Lostia S, Stuyver LJ, Watanabe KA, Chu CK, Schinazi RF, Otto MJ. Shi J, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):875-9. doi: 10.1081/ncn-200059224. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248053

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