Fletterick R - Search Results

1

Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.

Gasset M, Baldwin MA, Lloyd DH, Gabriel JM, Holtzman DM, Cohen F, Fletterick R, Prusiner SB. Gasset M, et al. Among authors: fletterick r. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10940-4. doi: 10.1073/pnas.89.22.10940. Proc Natl Acad Sci U S A. 1992. PMID: 1438300 Free PMC article.

2

High-level expression and characterization of a purified 142-residue polypeptide of the prion protein.

Mehlhorn I, Groth D, Stöckel J, Moffat B, Reilly D, Yansura D, Willett WS, Baldwin M, Fletterick R, Cohen FE, Vandlen R, Henner D, Prusiner SB. Mehlhorn I, et al. Among authors: fletterick r. Biochemistry. 1996 Apr 30;35(17):5528-37. doi: 10.1021/bi952965e. Biochemistry. 1996. PMID: 8611544

3

X-ray diffraction of scrapie prion rods and PrP peptides.

Nguyen JT, Inouye H, Baldwin MA, Fletterick RJ, Cohen FE, Prusiner SB, Kirschner DA. Nguyen JT, et al. Among authors: fletterick rj. J Mol Biol. 1995 Sep 29;252(4):412-22. doi: 10.1006/jmbi.1995.0507. J Mol Biol. 1995. PMID: 7563061

4

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

Pan KM, Baldwin M, Nguyen J, Gasset M, Serban A, Groth D, Mehlhorn I, Huang Z, Fletterick RJ, Cohen FE, et al. Pan KM, et al. Among authors: fletterick rj. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):10962-6. doi: 10.1073/pnas.90.23.10962. Proc Natl Acad Sci U S A. 1993. PMID: 7902575 Free PMC article.

5

Proposed three-dimensional structure for the cellular prion protein.

Huang Z, Gabriel JM, Baldwin MA, Fletterick RJ, Prusiner SB, Cohen FE. Huang Z, et al. Among authors: fletterick rj. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7139-43. doi: 10.1073/pnas.91.15.7139. Proc Natl Acad Sci U S A. 1994. PMID: 7913747 Free PMC article.

6

Spectroscopic characterization of conformational differences between PrPC and PrPSc: an alpha-helix to beta-sheet transition.

Baldwin MA, Pan KM, Nguyen J, Huang Z, Groth D, Serban A, Gasset M, Mehlhorn I, Fletterick RJ, Cohen FE, et al. Baldwin MA, et al. Among authors: fletterick rj. Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29;343(1306):435-41. doi: 10.1098/rstb.1994.0041. Philos Trans R Soc Lond B Biol Sci. 1994. PMID: 7913763

7

Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity.

Gasset M, Baldwin MA, Fletterick RJ, Prusiner SB. Gasset M, et al. Among authors: fletterick rj. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):1-5. doi: 10.1073/pnas.90.1.1. Proc Natl Acad Sci U S A. 1993. PMID: 8419912 Free PMC article.

8

Predicted secondary structure and membrane topology of the scrapie prion protein.

Bazan JF, Fletterick RJ, McKinley MP, Prusiner SB. Bazan JF, et al. Among authors: fletterick rj. Protein Eng. 1987 Feb-Mar;1(2):125-35. doi: 10.1093/protein/1.2.125. Protein Eng. 1987. PMID: 2907134

9

Structural clues to prion replication.

Cohen FE, Pan KM, Huang Z, Baldwin M, Fletterick RJ, Prusiner SB. Cohen FE, et al. Among authors: fletterick rj. Science. 1994 Apr 22;264(5158):530-1. doi: 10.1126/science.7909169. Science. 1994. PMID: 7909169 No abstract available.

10

Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.

Kanyo ZF, Pan KM, Williamson RA, Burton DR, Prusiner SB, Fletterick RJ, Cohen FE. Kanyo ZF, et al. Among authors: fletterick rj. J Mol Biol. 1999 Nov 5;293(4):855-63. doi: 10.1006/jmbi.1999.3193. J Mol Biol. 1999. PMID: 10543972

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