MacKeigan JP - Search Results

1

Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor.

Taxman DJ, MacKeigan JP, Clements C, Bergstralh DT, Ting JP. Taxman DJ, et al. Among authors: mackeigan jp. Cancer Res. 2003 Aug 15;63(16):5095-104. Cancer Res. 2003. PMID: 12941840

2

Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.

MacKeigan JP, Taxman DJ, Hunter D, Earp HS 3rd, Graves LM, Ting JP. MacKeigan JP, et al. Clin Cancer Res. 2002 Jul;8(7):2091-9. Clin Cancer Res. 2002. PMID: 12114408

3

Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.

MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP. MacKeigan JP, et al. Cancer Res. 2003 Oct 15;63(20):6928-34. Cancer Res. 2003. PMID: 14583493

4

MEK inhibition enhances paclitaxel-induced tumor apoptosis.

MacKeigan JP, Collins TS, Ting JP. MacKeigan JP, et al. J Biol Chem. 2000 Dec 15;275(50):38953-6. doi: 10.1074/jbc.C000684200. J Biol Chem. 2000. PMID: 11038347 Free article.

5

Combined gene expression profiling and RNAi screening in clear cell renal cell carcinoma identify PLK1 and other therapeutic kinase targets.

Ding Y, Huang D, Zhang Z, Smith J, Petillo D, Looyenga BD, Feenstra K, Mackeigan JP, Furge KA, Teh BT. Ding Y, et al. Among authors: mackeigan jp. Cancer Res. 2011 Aug 1;71(15):5225-34. doi: 10.1158/0008-5472.CAN-11-0076. Epub 2011 Jun 3. Cancer Res. 2011. PMID: 21642374

6

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

Monsma DJ, Cherba DM, Eugster EE, Dylewski DL, Davidson PT, Peterson CA, Borgman AS, Winn ME, Dykema KJ, Webb CP, MacKeigan JP, Duesbery NS, Nickoloff BJ, Monks NR. Monsma DJ, et al. Among authors: mackeigan jp. Am J Cancer Res. 2015 Mar 15;5(4):1507-18. eCollection 2015. Am J Cancer Res. 2015. PMID: 26101714 Free PMC article.

7

Down-regulation of class II phosphoinositide 3-kinase alpha expression below a critical threshold induces apoptotic cell death.

Elis W, Triantafellow E, Wolters NM, Sian KR, Caponigro G, Borawski J, Gaither LA, Murphy LO, Finan PM, Mackeigan JP. Elis W, et al. Among authors: mackeigan jp. Mol Cancer Res. 2008 Apr;6(4):614-23. doi: 10.1158/1541-7786.MCR-07-0262. Mol Cancer Res. 2008. PMID: 18403640

8

Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.

Lanning NJ, Castle JP, Singh SJ, Leon AN, Tovar EA, Sanghera A, MacKeigan JP, Filipp FV, Graveel CR. Lanning NJ, et al. Among authors: mackeigan jp. Cancer Metab. 2017 Aug 22;5:6. doi: 10.1186/s40170-017-0168-x. eCollection 2017. Cancer Metab. 2017. PMID: 28852500 Free PMC article.

9

A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

Murphy LO, MacKeigan JP, Blenis J. Murphy LO, et al. Among authors: mackeigan jp. Mol Cell Biol. 2004 Jan;24(1):144-53. doi: 10.1128/MCB.24.1.144-153.2004. Mol Cell Biol. 2004. PMID: 14673150 Free PMC article.

10

Kinase targets in renal-cell carcinomas: reassessing the old and discovering the new.

Furge KA, MacKeigan JP, Teh BT. Furge KA, et al. Among authors: mackeigan jp. Lancet Oncol. 2010 Jun;11(6):571-8. doi: 10.1016/S1470-2045(09)70380-8. Epub 2010 Apr 8. Lancet Oncol. 2010. PMID: 20381423 Review.

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