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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma.
Phan GQ, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Restifo NP, Haworth LR, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, Duray PH, Steinberg SM, Allison JP, Davis TA, Rosenberg SA. Phan GQ, et al. Among authors: allison jp. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8372-7. doi: 10.1073/pnas.1533209100. Epub 2003 Jun 25. Proc Natl Acad Sci U S A. 2003. PMID: 12826605 Free PMC article. Clinical Trial.
Thymocyte development is normal in CTLA-4-deficient mice.
Chambers CA, Cado D, Truong T, Allison JP. Chambers CA, et al. Among authors: allison jp. Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9296-301. doi: 10.1073/pnas.94.17.9296. Proc Natl Acad Sci U S A. 1997. PMID: 9256476 Free PMC article.
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation.
van Elsas A, Hurwitz AA, Allison JP. van Elsas A, et al. Among authors: allison jp. J Exp Med. 1999 Aug 2;190(3):355-66. doi: 10.1084/jem.190.3.355. J Exp Med. 1999. PMID: 10430624 Free PMC article.
363 results