Dobrzynski E - Search Results

1

Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.

Mingozzi F, Liu YL, Dobrzynski E, Kaufhold A, Liu JH, Wang Y, Arruda VR, High KA, Herzog RW. Mingozzi F, et al. Among authors: dobrzynski e. J Clin Invest. 2003 May;111(9):1347-56. doi: 10.1172/JCI16887. J Clin Invest. 2003. PMID: 12727926 Free PMC article.

2

Major role of local immune responses in antibody formation to factor IX in AAV gene transfer.

Wang L, Cao O, Swalm B, Dobrzynski E, Mingozzi F, Herzog RW. Wang L, et al. Among authors: dobrzynski e. Gene Ther. 2005 Oct;12(19):1453-64. doi: 10.1038/sj.gt.3302539. Gene Ther. 2005. PMID: 15889137

3

Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer.

Dobrzynski E, Mingozzi F, Liu YL, Bendo E, Cao O, Wang L, Herzog RW. Dobrzynski E, et al. Blood. 2004 Aug 15;104(4):969-77. doi: 10.1182/blood-2004-03-0847. Epub 2004 Apr 22. Blood. 2004. PMID: 15105293 Free article.

4

Immune implications of gene therapy for hemophilia.

Herzog RW, Dobrzynski E. Herzog RW, et al. Among authors: dobrzynski e. Semin Thromb Hemost. 2004 Apr;30(2):215-26. doi: 10.1055/s-2004-825635. Semin Thromb Hemost. 2004. PMID: 15118933 Review.

5

Therapeutic levels of factor IX expression using a muscle-specific promoter and adeno-associated virus serotype 1 vector.

Liu YL, Mingozzi F, Rodriguéz-Colôn SM, Joseph S, Dobrzynski E, Suzuki T, High KA, Herzog RW. Liu YL, et al. Among authors: dobrzynski e. Hum Gene Ther. 2004 Aug;15(8):783-92. doi: 10.1089/1043034041648453. Hum Gene Ther. 2004. PMID: 15319035

6

Systemic protein delivery by muscle-gene transfer is limited by a local immune response.

Wang L, Dobrzynski E, Schlachterman A, Cao O, Herzog RW. Wang L, et al. Among authors: dobrzynski e. Blood. 2005 Jun 1;105(11):4226-34. doi: 10.1182/blood-2004-03-0848. Epub 2005 Feb 15. Blood. 2005. PMID: 15713796 Free PMC article.

7

Tolerance induction by viral in vivo gene transfer.

Dobrzynski E, Herzog RW. Dobrzynski E, et al. Clin Med Res. 2005 Nov;3(4):234-40. doi: 10.3121/cmr.3.4.234. Clin Med Res. 2005. PMID: 16303889 Free PMC article. Review.

8

Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells.

Dobrzynski E, Fitzgerald JC, Cao O, Mingozzi F, Wang L, Herzog RW. Dobrzynski E, et al. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4592-7. doi: 10.1073/pnas.0508685103. Epub 2006 Mar 10. Proc Natl Acad Sci U S A. 2006. PMID: 16537361 Free PMC article.

9

Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer.

Cao O, Dobrzynski E, Wang L, Nayak S, Mingle B, Terhorst C, Herzog RW. Cao O, et al. Among authors: dobrzynski e. Blood. 2007 Aug 15;110(4):1132-40. doi: 10.1182/blood-2007-02-073304. Epub 2007 Apr 16. Blood. 2007. PMID: 17438084 Free PMC article.

10

Muscle as a target for supplementary factor IX gene transfer.

Hoffman BE, Dobrzynski E, Wang L, Hirao L, Mingozzi F, Cao O, Herzog RW. Hoffman BE, et al. Among authors: dobrzynski e. Hum Gene Ther. 2007 Jul;18(7):603-13. doi: 10.1089/hum.2007.042. Hum Gene Ther. 2007. PMID: 17594244

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