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Inactivation of E2F3 results in centrosome amplification.
Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G. Saavedra HI, et al. Among authors: maiti b. Cancer Cell. 2003 Apr;3(4):333-46. doi: 10.1016/s1535-6108(03)00083-7. Cancer Cell. 2003. PMID: 12726860 Free PMC article.
The E2F1-3 transcription factors are essential for cellular proliferation.
Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: maiti b. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808
350 results