Ghanekar SV - Search Results

1

The mechanism of gamma-secretase: multiple inhibitor binding sites for transition state analogs and small molecule inhibitors.

Tian G, Ghanekar SV, Aharony D, Shenvi AB, Jacobs RT, Liu X, Greenberg BD. Tian G, et al. Among authors: ghanekar sv. J Biol Chem. 2003 Aug 1;278(31):28968-75. doi: 10.1074/jbc.M300905200. Epub 2003 Apr 28. J Biol Chem. 2003. PMID: 12719412 Free article.

2

Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?

Knappenberger KS, Tian G, Ye X, Sobotka-Briner C, Ghanekar SV, Greenberg BD, Scott CW. Knappenberger KS, et al. Among authors: ghanekar sv. Biochemistry. 2004 May 25;43(20):6208-18. doi: 10.1021/bi036072v. Biochemistry. 2004. PMID: 15147205

3

Novel small molecule inhibitors of caspase-3 block cellular and biochemical features of apoptosis.

Scott CW, Sobotka-Briner C, Wilkins DE, Jacobs RT, Folmer JJ, Frazee WJ, Bhat RV, Ghanekar SV, Aharony D. Scott CW, et al. Among authors: ghanekar sv. J Pharmacol Exp Ther. 2003 Jan;304(1):433-40. doi: 10.1124/jpet.102.039651. J Pharmacol Exp Ther. 2003. PMID: 12490620

4

Pharmacological characterization of ZD6021: a novel, orally active antagonist of the tachykinin receptors.

Rumsey WL, Aharony D, Bialecki RA, Abbott BM, Barthlow HG, Caccese R, Ghanekar S, Lengel D, McCarthy M, Wenrich B, Undem B, Ohnmacht C, Shenvi A, Albert JS, Brown F, Bernstein PR, Russell K. Rumsey WL, et al. J Pharmacol Exp Ther. 2001 Jul;298(1):307-15. J Pharmacol Exp Ther. 2001. PMID: 11408556

5

Pharmacological characterization of a new class of nonpeptide neurokinin A antagonists that demonstrate species selectivity.

Aharony D, Buckner CK, Ellis JL, Ghanekar SV, Graham A, Kays JS, Little J, Meeker S, Miller SC, Undem BJ, et al. Aharony D, et al. Among authors: ghanekar sv. J Pharmacol Exp Ther. 1995 Sep;274(3):1216-21. J Pharmacol Exp Ther. 1995. PMID: 7562491

6

Pharmacological examination of receptors mediating contractile responses to tachykinins in airways isolated from human, guinea pig and hamster.

Ellis JL, Undem BJ, Kays JS, Ghanekar SV, Barthlow HG, Buckner CK. Ellis JL, et al. Among authors: ghanekar sv. J Pharmacol Exp Ther. 1993 Oct;267(1):95-101. J Pharmacol Exp Ther. 1993. PMID: 8229792

7

Pharmacological studies of tachykinin receptors mediating contraction of isolated airway smooth muscle.

Buckner CK, Ghanekar SV, Kays JS, Krell RD, Fishleder RI, Will JA, Vann JM. Buckner CK, et al. Among authors: ghanekar sv. Ann N Y Acad Sci. 1991;629:340-58. doi: 10.1111/j.1749-6632.1991.tb37988.x. Ann N Y Acad Sci. 1991. PMID: 1719852 No abstract available.

8

[³H]Chiba-1001(methyl-SSR180711) has low in vitro binding affinity and poor in vivo selectivity to nicotinic alpha-7 receptor in rodent brain.

Ding M, Ghanekar S, Elmore CS, Zysk JR, Werkheiser JL, Lee CM, Liu J, Chhajlani V, Maier DL. Ding M, et al. Synapse. 2012 Apr;66(4):315-22. doi: 10.1002/syn.21513. Epub 2011 Dec 29. Synapse. 2012. PMID: 22108786

9

A monoclonal antibody that identifies mature T lymphocytes of cattle.

Rossi CR, Campos M, Ghanekar SV, Panangala VS. Rossi CR, et al. Among authors: ghanekar sv. Vet Immunol Immunopathol. 1986 Apr;11(4):319-24. doi: 10.1016/0165-2427(86)90034-6. Vet Immunol Immunopathol. 1986. PMID: 3521066

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