Fischer DS - Search Results

1

D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase.

Fischer DS, Woo LW, Mahon MF, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Bioorg Med Chem. 2003 Apr 17;11(8):1685-700. doi: 10.1016/s0968-0896(03)00042-7. Bioorg Med Chem. 2003. PMID: 12659755

2

Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.

Fischer DS, Chander SK, Woo LW, Fenton JC, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):343-9. doi: 10.1016/s0960-0760(03)00048-7. J Steroid Biochem Mol Biol. 2003. PMID: 12711021

3

E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Fischer DS, Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Wood L, Packham G, Mahon MF, Reed MJ, Potter BV. Fischer DS, et al. J Med Chem. 2005 Sep 8;48(18):5749-70. doi: 10.1021/jm050348a. J Med Chem. 2005. PMID: 16134943

4

Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Lawrence HR, Cornet J, Bubert C, Fischer DS, Vicker N, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Allan GM, et al. Among authors: fischer ds. J Med Chem. 2006 Feb 23;49(4):1325-45. doi: 10.1021/jm050830t. J Med Chem. 2006. PMID: 16480268

5

Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography.

Woo LW, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BV. Woo LW, et al. Among authors: fischer ds. Mol Cancer Ther. 2008 Aug;7(8):2435-44. doi: 10.1158/1535-7163.MCT-08-0195. Mol Cancer Ther. 2008. PMID: 18723489 Free article.

6

The regulation and inhibition of 17beta-hydroxysteroid dehydrogenase in breast cancer.

Purohit A, Tutill HJ, Day JM, Chander SK, Lawrence HR, Allan GM, Fischer DS, Vicker N, Newman SP, Potter BV, Reed MJ. Purohit A, et al. Among authors: fischer ds. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):199-203. doi: 10.1016/j.mce.2005.12.003. Epub 2006 Jan 18. Mol Cell Endocrinol. 2006. PMID: 16414180

7

Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

Inglis SR, Zervosen A, Woon EC, Gerards T, Teller N, Fischer DS, Luxen A, Schofield CJ. Inglis SR, et al. Among authors: fischer ds. J Med Chem. 2009 Oct 8;52(19):6097-106. doi: 10.1021/jm9009718. J Med Chem. 2009. PMID: 19731939

8

scTab: Scaling cross-tissue single-cell annotation models.

Fischer F, Fischer DS, Mukhin R, Isaev A, Biederstedt E, Villani AC, Theis FJ. Fischer F, et al. Among authors: fischer ds. Nat Commun. 2024 Aug 4;15(1):6611. doi: 10.1038/s41467-024-51059-5. Nat Commun. 2024. PMID: 39098889 Free PMC article.

9

Predicting preferred motorcycle riding postures to support human factors/ergonomic trade-off analyses within a multi-objective optimisation-based digital human model.

Davidson JB, Fischer DSL. Davidson JB, et al. Among authors: fischer dsl. Ergonomics. 2024 Mar 18:1-15. doi: 10.1080/00140139.2024.2329694. Online ahead of print. Ergonomics. 2024. PMID: 38497206

10

Modeling fragment counts improves single-cell ATAC-seq analysis.

Martens LD, Fischer DS, Yépez VA, Theis FJ, Gagneur J. Martens LD, et al. Among authors: fischer ds. Nat Methods. 2024 Jan;21(1):28-31. doi: 10.1038/s41592-023-02112-6. Epub 2023 Dec 4. Nat Methods. 2024. PMID: 38049697 Free PMC article.

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