Pathak VK - Search Results

1

Azido-containing aryl beta-diketo acid HIV-1 integrase inhibitors.

Zhang X, Pais GC, Svarovskaia ES, Marchand C, Johnson AA, Karki RG, Nicklaus MC, Pathak VK, Pommier Y, Burke TR. Zhang X, et al. Among authors: pathak vk. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1215-9. doi: 10.1016/s0960-894x(03)00059-3. Bioorg Med Chem Lett. 2003. PMID: 12643946

2

Development of an in vivo assay to identify structural determinants in murine leukemia virus reverse transcriptase important for fidelity.

Halvas EK, Svarovskaia ES, Pathak VK. Halvas EK, et al. Among authors: pathak vk. J Virol. 2000 Jan;74(1):312-9. J Virol. 2000. PMID: 10590119 Free PMC article.

3

Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine.

Halvas EK, Svarovskaia ES, Freed EO, Pathak VK. Halvas EK, et al. Among authors: pathak vk. J Virol. 2000 Jul;74(14):6669-74. doi: 10.1128/jvi.74.14.6669-6674.2000. J Virol. 2000. PMID: 10864683 Free PMC article.

4

Structural determinants of murine leukemia virus reverse transcriptase that affect the frequency of template switching.

Svarovskaia ES, Delviks KA, Hwang CK, Pathak VK. Svarovskaia ES, et al. Among authors: pathak vk. J Virol. 2000 Aug;74(15):7171-8. doi: 10.1128/jvi.74.15.7171-7178.2000. J Virol. 2000. PMID: 10888659 Free PMC article.

5

Role of murine leukemia virus reverse transcriptase deoxyribonucleoside triphosphate-binding site in retroviral replication and in vivo fidelity.

Halvas EK, Svarovskaia ES, Pathak VK. Halvas EK, et al. Among authors: pathak vk. J Virol. 2000 Nov;74(22):10349-58. doi: 10.1128/jvi.74.22.10349-10358.2000. J Virol. 2000. PMID: 11044079 Free PMC article.

6

Dynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching.

Hwang CK, Svarovskaia ES, Pathak VK. Hwang CK, et al. Among authors: pathak vk. Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12209-14. doi: 10.1073/pnas.221289898. Epub 2001 Oct 2. Proc Natl Acad Sci U S A. 2001. PMID: 11593039 Free PMC article.

7

Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

Pais GC, Zhang X, Marchand C, Neamati N, Cowansage K, Svarovskaia ES, Pathak VK, Tang Y, Nicklaus M, Pommier Y, Burke TR Jr. Pais GC, et al. Among authors: pathak vk. J Med Chem. 2002 Jul 18;45(15):3184-94. doi: 10.1021/jm020037p. J Med Chem. 2002. PMID: 12109903

8

Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts.

Zhang WH, Svarovskaia ES, Barr R, Pathak VK. Zhang WH, et al. Among authors: pathak vk. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10090-5. doi: 10.1073/pnas.152186199. Epub 2002 Jul 15. Proc Natl Acad Sci U S A. 2002. PMID: 12119402 Free PMC article.

9

Retroviral mutation rates and reverse transcriptase fidelity.

Svarovskaia ES, Cheslock SR, Zhang WH, Hu WS, Pathak VK. Svarovskaia ES, et al. Among authors: pathak vk. Front Biosci. 2003 Jan 1;8:d117-34. doi: 10.2741/957. Front Biosci. 2003. PMID: 12456349 Review.

10

Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions.

Svarovskaia ES, Barr R, Zhang X, Pais GC, Marchand C, Pommier Y, Burke TR Jr, Pathak VK. Svarovskaia ES, et al. Among authors: pathak vk. J Virol. 2004 Apr;78(7):3210-22. doi: 10.1128/jvi.78.7.3210-3222.2004. J Virol. 2004. PMID: 15016842 Free PMC article.

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