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Functional interactions between the alpha1b-adrenoceptor and Galpha11 are compromised by de-palmitoylation of the G protein but not of the receptor.
Novotny J, Durchankova D, Ward RJ, Carrillo JJ, Svoboda P, Milligan G. Novotny J, et al. Among authors: milligan g. Cell Signal. 2006 Aug;18(8):1244-51. doi: 10.1016/j.cellsig.2005.10.004. Epub 2005 Nov 16. Cell Signal. 2006. PMID: 16297597
Both the alpha1b-adrenoceptor and Galpha11 are targets for post-translational thio-acylation that is regulated by agonist occupancy of the receptor [P.A. Stevens, J. Pediani, J.J. Carrillo, G. Milligan, J. Biol. Chem. 276 (2001) 35883]. In co-expression studies muta …
Both the alpha1b-adrenoceptor and Galpha11 are targets for post-translational thio-acylation that is regulated by agonist occupancy of the r …
Agonist-induced transfer of the alpha subunits of the guanine-nucleotide-binding regulatory proteins Gq and G11 and of muscarinic m1 acetylcholine receptors from plasma membranes to a light-vesicular membrane fraction.
Svoboda P, Milligan G. Svoboda P, et al. Among authors: milligan g. Eur J Biochem. 1994 Sep 1;224(2):455-62. doi: 10.1111/j.1432-1033.1994.00455.x. Eur J Biochem. 1994. PMID: 7925360 Free article.
W., Buckley, N. J. & Milligan, G. (1993) Biochem. J. 289, 125-131]. To examine early events in this process, the effect of agonist on subcellular distribution of Gq alpha and G11 alpha and of Hm1 receptors was assessed after short-term and long-term treatment wi …
W., Buckley, N. J. & Milligan, G. (1993) Biochem. J. 289, 125-131]. To examine early events in this process, the effect of …
783 results