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Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity.
Fisher TS, Kamperschroer C, Oliphant T, Love VA, Lira PD, Doyonnas R, Bergqvist S, Baxi SM, Rohner A, Shen AC, Huang C, Sokolowski SA, Sharp LL. Fisher TS, et al. Among authors: love va. Cancer Immunol Immunother. 2012 Oct;61(10):1721-33. doi: 10.1007/s00262-012-1237-1. Epub 2012 Mar 11. Cancer Immunol Immunother. 2012. PMID: 22406983 Free PMC article.